Richter Gedeon Vegyeszeti Gyar Rt

Ilona Hermann Nee Szente

Janos Borvendeg

Inge Schafer

Katalin Szilagyi Nee Farago

Eleonora Szondy

Sandor Solyom

Lajos Toldy

Imre Moravcsik

Gyula Horvath

Lajos Toldi

Pal Bite

Zsuzsanna Mehesfalvi Nee Vajna

Sandor S Toldy

New steroid-spiro-oxathiazolidine derivatives pharmaceutical compositions containing the same, and to a process for the preparation thereof are disclosed. The new compounds have antimineral corticoide effects and have the following formula (I), ##STR1## wherein R.sub.1 is a C.sub.1-3 alkyl or a C.sub.2-4 alkenyl group, and

Steroid-spiro-oxathiazolidine derivatives and a process for the

Compounds of the formula (I) having aldosterone-antagonizing activity are disclosed ##STR1## wherein R.sub.3 and R.sub.4 are each C.sub.1 to C.sub.3 alkyl; and

Substituted steroid-spiro-oxazolidinone derivatives and a process for

Diuretic pharmaceutically active steroid-spiro-oxazolidinone compounds of the formula (I), ##STR1## wherein R.sup.1 is hydrogen or methyl,

The invention relates to novel spirooxazolidines represented by the formula I ##STR1## wherein R.sub.1 is alkyl having from 1 to 4 carbon atoms;

Novel steroidspirooxazolidines and process for their preparation

Novel 6-amino-5.alpha.,19-cycloandrostane derivatives of formula I and their pharmaceutically acceptable addition salts ##STR1## wherein X denotes any of the groups of the formula =CH(OR), =CO or =C=N-OR.sub.1,

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Budapest, Hungary

Ilona Hermann Nee Szente