Korea Research Institute of Chemical Technology

Korea Research Institute of Bioscience and Biotechnology

St Pharm Co., Ltd.

Farmhannong Co., Ltd.

Moghu Research Center Ltd

Ill Young Lee

Jong Chan Son

Michael L Mitchell

Hongyan Guo

Choung U Kim

Lianhong Xu

Jae Hak Kim

Sang Ho Lee

Thorsten A Kirschberg

Jae Wook Ryu

Bong Jin Kim

Chang Soo Yun

Steven S Pfeiffer

Chong Ock Lee

Jee Hee Suh

Young Kwan Ko

Hyun Jin Kim

Kyungjin Kim

Semi Kim

Dong Wan Koo

Chong-Kyo Lee

Gyu Hwan Yon

Nack Jeong Kim

Pilho Kim

So-Young Lee

Jae Deok Kim

Uk-Il Kim

Suk-Jin Koo

Mi Sook Hong

Ah Reum Kim

Chong Kgo Lee

Stacey Heumann

Ki-Hwan Hwang

Eun-Hee Nam

Nam-Gyu Cho

Jisoo Lim

Junhyuk Choi

Jung Sub Choi

Hye Ji Han

Sungjun Park

Chan Yong Park

Byung Hoon Ahn

Yun Kyoung Hwang

Seungae Oh

Eun Ae Kim

Hye-Jin Min

Dong Joon Ko

Hyun Suk Yeom

Jong-Su Lim

Gerry Rhodes

Dong-Guk Lee

Hwa Jung Nam

Hong Suk Shin

Hee Nam Lim

Mi-Young Kwak

Sung-Hun Kim

Jun-Ho Nam

Kun-Hoe Chung

The present invention relates to a novel nicotinamide compound, a method for preparing the same, and a herbicide comprising the compound. The compound of the present invention is useful as a herbicide for foliar treatment or soil treatment because it has high safety for wheat or corn and has excellent herbicidal activity against grassy weeds, sedge weeds or broadleaf weeds.

Nicotinamide compound and herbicidal composition comprising compound

Provided is a novel pyrrolopyridine compound represented by Chemical Formula I, a racemate or a stereoisomer thereof, or a pharmaceutically acceptable salt thereof; and to a method for preparing the same. A compound represented by Chemical Formula I shows high selectivity and antiviral activity against human immunodeficiency virus (HIV), with low toxicity; therefore, it is useful as a therapeutic agent for viral infection, in particular, HIV infection.

Pyrrolopyridine derivative, method for producing same, and use thereof

The present invention relates to a pyrrolopyridine derivative represented by the Chemical Formula I, and a racemate or a stereoisomer thereof, or a pharmaceutically acceptable salt thereof, and relates to an antiviral composition including the same as an active ingredient. The compound of the Chemical Formula I has excellent antiviral activity and selectivity for wild type and resistant HIV-1, and thereby is useful as a therapeutic agent for acquired immune deficiency syndrome (AIDS).

Antiviral pyrrolopyridine derivatives and method for preparing the same

The present invention relates to a 2-hydroxyarylamide derivative or a pharmaceutically acceptable salt thereof, a preparation method thereof, and a pharmaceutical composition for preventing or treating cancer comprising the same as an active ingredient. The 2-hydroxyarylamide derivative prepared by the present invention is excellent in the inhibition of the activity of TMPRSS4 serine protease and the suppression of the infiltration of TMPRSS4-expressed cancer cells, and thus can be useful as a composition for preventing or treating cancer by inhibiting TMPRSS4 over-expressed in cancer cells, particularly, colorectal cancer, lung cancer, breast cancer, prostate cancer, ovarian cancer, pancreatic cancer, or stomach cancer cells.

2-hydroxyarylamide derivative or pharmaceutically acceptable salt thereof, preparation method thereof, and pharmaceutical composition for preventing or treating cancer containing same as active ingredient

The invention is related to compounds of Formula (I): or a pharmaceutically acceptable salt, solvate, ester, and/or phosphonate thereof, compositions containing such compounds, and therapeutic methods that include the administration of such compounds.

Pyrimidine derivatives as HIV reverse transcriptase inhibitors

Compounds of Formula (I): can be prepared by a multi-step process from compounds of Formula (II): wherein G is Cl, Br or I.

Processes for preparing HIV reverse transcriptase inhibitors

The invention is related to pyrimidine-2,4-dione HIV reverse transcriptase inhibitors of Formula (I), (II), or (III): or a pharmaceutically acceptable salt, thereof, compositions containing such compounds, and therapeutic methods that include the administration of such compounds.

Pyrimidine-2,4-dione HIV reverse transcriptase inhibitors

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Daejeon, South Korea

Ill Young Lee