Università Degli Studi Di Ferrara

Associazione Veneta Per La Lotta Alla Talassemia

Rare Partners Srl

Ilaria Lampronti

Roberto Gambari

Nicoletta Bianchi

Monica Borgatti

Daniele Simoni

The invention refers to the use of isoxazole derivatives to prepare medicament able to induce fetal hemoglobin (HbF) synthesis in &#x3b2;-thalassemia and sickle cell disease (SCD) patients.

Isoxazole derivatives as inducers of fetal hemoglobin in erythroid precursor cells from beta-thalassemic patients

The use of angelicin and its structural analogues for the preparation of a medicament for the therapeutic treatment of beta-thalassaemia is described. A structural analogue which is particularly preferred for this purpose is bergapten.

Use of angelicin and of its structural analogues for the treatment of thalassemia

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Milan, Italy

Ilaria Lampronti