The Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center

Yeda Research and Develpment & Co. Ltd

Ilan Volovitz

Zvi Ram

Gil Diamant

Merav Lustgarten

Netanel Yakov Shapira

Idan Ben Horin

Irun R Cohen

Lea Eisenbach

Shimon Slavin

Provided relates to the field of cytometry, specifically to flow cytometric methods and kits for improved diagnosis, prognosis and monitoring of tumors and other lesions involving immune cell infiltration. Further provided are embodiments of the subject matter which relate to compositions and methods providing high resolution quantitative means for immunophenotyping and immune modeling, and for identification of disease prognostic and therapy predictive biomarkers.

Cytometric assays

A method of treating cancer in an immune-privileged site of a subject in need thereof is provided. The method comprises systemically administering to an area outside the immune-privileged site of the subject, a therapeutically effective amount of naive, viable cells of a tumor of the subject, the tumor being in the immune-privileged site so as to generate an immune response in the subject, thereby treating the cancer in the immune-privileged site of the subject.

Methods of treating tumors in immune-privileged sites

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Tel Aviv, Israel

Ilan Volovitz