Otsuka Pharmaceutical Company, Limited

Amino Up Co., Ltd.

Ikutaro Sato

Takashi Hayashi

Masayuki Takahashi

Yasuhiro Abiru

Yoshikazu Shimada

Tadaaki Ohtani

Norihiro Miyazawa

Setsuko Yasuda

Noriyuki Kouda

Kazunori Goto

Jun Nakahigashi

Atsuya Sato

Yosuke Hirayama

Moeri Horikoshi

Syoichiro Inoue

Manami Kato

Masahiro Oono

Hiroyuki Kimura

Shigeto Uchiyama

Tomomi Ueno

Kentaro Tadano

Takeshi Yamauchi

Toshimi Suzuki

Masatoshi Mizuno

Provided is a heat shock protein expression-inducing agent, more specifically, a heat shock protein expression-inducing agent comprising a compound represented by formula (I): wherein R is a lower alkyl, phenyl, or hydroxyphenyl, or a salt thereof.

Sleep improving agent

The present invention provides a heat shock protein expression-inducing agent, more specifically, a heat shock protein expression-inducing agent comprising a compound represented by formula (I): wherein R is a lower alkyl, phenyl, or hydroxyphenyl, or a salt thereof.

An object of the invention is to provide an equol-containing fermented soybean hypocotyl material that is useful for foods, pharmaceutical preparations, cosmetic products, etc. The equol-containing fermented soybean hypocotyl material of the invention is obtained by fermenting soybean hypocotyls using at least one microorganism having an equol-producing ability by utilizing at least one daidzein compound selected from the group consisting of diadzein glycosides, daidzein, and dihydrodaidzein.

Equol-containing fermentation product of soybean embryonic axis, and method for production thereof

An object of the present invention is to provide enzymes associated with equol synthesis, genes coding such enzymes, and a process for producing equol and its intermediates using the enzymes and genes. The present invention provides a dihydrodaidzein synthesizing enzyme, tetrahydrodaidzein synthesizing enzyme, equol synthesizing enzyme, and genes coding these enzymes. The present invention also provides a process for synthesizing dihydrodaidzein, tetrahydrodaidzein, and/or equol using these enzymes.

Enzyme associated with equol synthesis

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Osaka, Japan

Ikutaro Sato