Other

Juridical Foundation the Chemo-sero-therapeutic Research Institute

Meiji Seika Kaisha, Ltd.

Meji Seika Kaisha Ltd.

Meui Seika Kaisha, Ltd.

Meiji Seika Kaisya Ltd.

Ikuo Igarashi

Kozo Fujisaki

Hideyuki Nagasawa

Naotoshi Tsuji

Hiroshi Suzuki

Chihiro Sugimoto

Gakunan Gen

Noboru Inoue

Naoaki Yokoyama

Kimie Kadota

Takeshi Mikami

Hiromi Ikadai

Naoyoshi Suzuki

Myonjo Yu

A novel galectin, a polynucleotide encoding the same, a vector and a transformant comprising the polynucleotide, an antibody against the galectin, and a screening method for screening a substance capable of modifying the galectin, are disclosed. According to the galectin, polynucleotide, or vector, it is possible, for example, to exterminate ticks, or to treat or prevent tick-borne infections such as rickettsiosis, filariasis, Q fever, African recurrent fever, or viral encephalitis.

Tick galectin

A novel chitinase, a polynucleotide encoding the same, a vector and a transformant comprising the polynucleotide, an antibody against the chitinase, and a screening method for screening a substance capable of modifying the chitinase, are disclosed. According to the chitinase, polynucleotide, or vector, it is possible, for example, to exterminate ticks, or to treat or prevent tick-borne infections such as piroplasmosis, Q fever, or viral encephalitis.

Tick chitinase

The present invention provides a gene encoding a protein from merozoite of, a recombinant protein of, and an antibody capable specifically binding to a 48 kDa protein of rhoptry ofmerozoite. In accordance with the present invention, it is possible to stably prepare the 48 kDa protein of rhoptry ofand the gene encoding said protein in a large amount with the recombinant DNA technique. The present invention also provides a method for diagnosing equine babesiasis which comprises either specifically detecting anti-antibody present in equine blood by using the recombinant protein of present invention as an antigen or detecting the presence ofmerozoite in equine blood by using the antibody of the present invention.

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Mite galectin

The present invention provides a gene encoding a protein from merozoite of, a recombinant protein of, and an antibody capable specifically binding to a 48 kDa protein of rhoptry ofmerozoite. In accordance with the present invention, it is possible to stably prepare the 48 kDa protein of rhoptry ofand the gene encoding said protein in a large amount with the recombinant DNA technique. The present invention also provides a method for diagnosing equine babesiasis which comprises either specifically detecting anti-antibody present in equine blood by using the recombinant protein of present invention as an .antigen or detecting the presence ofmerozoite in equine blood by using the antibody of the present invention.

Gene encoding merozoite protein of Babesia caballi, recombinant protein obtained therefrom and utilization thereof

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Hokkaido, Japan

Ikuo Igarashi