Ethicon, Gmbh

Cordis Corporation

Depuy Mitek, Inc.

Depuy Synthes Products, Inc.

Depuy Products, Inc.

Janssen Sciences Ireland Unlimited Company

Ethicon Endo-Surgery, Inc.

The University of Akron

Codman & Shurtleff, Inc.

Janssen R&d Ireland

Janssen Sciences Ireland Uc

Cardinal Health Switzerland 515 Gmbh

Advanced Technologies and Regenerative Medicine, LLC

Struktol Company of America, LLC

Iksoo Chun

Mora Carolynne Melican

Kelly R Brown

Mark B Roller

Alireza Rezania

Dennis D Jamiolkowski

David Christopher Majercak

Yufu Li

Angelo G Scopelianos

Chunlin Yang

Murty Narayan Vyakarnam

Lieven Elvire Colette Baert

Qiang Zhang

Mark C Zimmerman

Deborah M Schachter

Guenter Kraus

Hassan A Serhan

Michael Alan Fisher

Prasanna Malaviya

Jeffrey Karl Sutton

Sridevi N Dhanaraj

Paul Joseph Birkmeyer

Uri Herzberg

Raymond S Shissias

David V Gorky

Clairene A Bazilio

Chester O Baxter, Iii

Charles J Scheib

Taylor W Aronhalt

Richard L Leimbach

Rao S Bezwada

Jeffrey L Aldridge

Sean P Conlon

Darren R Sherman

Michael S Cropper

Joshua R Uth

Donna L Korvick

Anna Gosiewska

Kevin L Cooper

Christopher J Schall

Darrell H Reneker

Julia Hwang

Vipul Bhupendra Dave

Francois Binette

Agnieszka Seyda

Victor F Janas

Venkataramanan Mandakolathur Vasudevan

Laura Brown

Joseph J Hammer

Hiep Quang Do

David C Colter

Richard Champion Davis, Iii

Hiep Do

Woraphon Kataphinan

Carrie H Fang

John McAllen, Iii

Dale Ertley

Mike Mikolay

Hollie Kennedy

Li Zhang

Matthew Gounis

Jennifer Mandanas

Dhanuraj S Shetty

Thomas Patrick Hyland

Lieven Elvire Baert

Iii Chester O Baxter

Angelo G Scopellianos

Mcallen Iii John John

Richard Champion Davis Iii

Zoran Brdarski

Mechanical modifications to a spinal rod that will enable the rod to accept various coating technologies in such a way that the spinal construct's biomechanical performance is not compromised. These modifications preserve construct biomechanics in the presence of a coating and increase the bactericidal payload of an anti-infective spinal rod coating.

Anti-infective orthopedic implant

A degradable, removable, pharmaceutical implant for the sustained release of one or more drugs in a subject, wherein the pharmaceutical implant is composed of a tube comprising an outer wall made of a degradable polymer completely surrounding a cavity, wherein the outer wall has a plurality of openings and wherein the cavity contains one or more sets of micro-particles, which micro-particles contain an active agent or a combination of two or more active agents, and wherein the size of the microparticles is selected such that the majority of the microparticles cannot pass through the openings.

Degradable removable implant for the sustained release of an active compound

Anti-infective spinal rod with surface features

A tissue thickness compensator can comprise a plurality of layers. Various embodiments are disclosed herein for manufacturing a tissue thickness compensator. In certain embodiments, a tissue thickness compensator can comprise at least one medicament tube, capsule, and/or packet contained therein.

Tissue thickness compensator comprising a plurality of capsules

Compositions and methods of using tissue engineered blood vessels to repair and regenerate blood vessels of patients with vascular disease are disclosed.

Tissue engineered blood vessel

A biocompatible tissue implant. The tissue implant may be bioabsorbable, consists of a biocompatible polymeric foam. The tissue implant also includes a biocompatible reinforcement member. The polymeric foam and the reinforcement member are soluble in a lyophilizing solvent. The reinforcement may be annealed and/or coated.

Method of preparation of bioabsorbable porous reinforced tissue implants and implants thereof

The present invention relates to a medical device and method of forming the medical device. In particular, the present invention relates to a medical device having a tubular membrane structure over a radially expandable structural frame, and to a method of forming the tubular membrane on the radially expandable structural frame. In one aspect, a structural frame is placed over a spinning mandrel and a fiber is electro-statically spun over at least a portion of the structural frame forming a membrane. A transfer sheath may be used between the mandrel and structural frame to prevent the electro-statically spun fiber from adhering to the mandrel. In another aspect, a first membrane is spun over the mandrel before the structural frame is placed over the mandrel. In this aspect, at least a portion of the structural frame is sandwiched between the membranes. The membrane or membranes and structural frame form a fiber spun frame assembly. The fiber spun frame assembly may be coated with an elastic polymer. In addition, the membrane or membranes may go through some post processing to achieve desired characteristics or configurations.

Method of forming a tubular membrane on a structural frame

A bioprosthetic device is provided for soft tissue attachment, reinforcement, and or reconstruction. The device comprises a naturally occurring extracellular matrix portion and a three-dimensional synthetic portion. In illustrated embodiments, the naturally occurring extracellular matrix portion comprises layers of small intestine submucosa, and the three-dimensional synthetic portion comprises a foam or a three-dimensional mesh, textile, or felt.

Hybrid biologic-synthetic bioabsorbable scaffolds

Vaso-occlusive devices are provided that have a polymer foam disposed about them. The polymer is treated with a plasma to facilitate thrombogenicity. A method for making and using such devices also is provided. The preferred polymer is a copolymer of a halogenated vinylidene and a halogenated alkene.

Plasma-treated vascular occlusion devices and methods

Methods of making a hybrid biologic/synthetic scaffold for repairing damaged or diseased tissue are provided. The methods include the step of suspending pieces of an extracellular matrix material in a liquid to form a slurry, and coating a synthetic mat with the slurry, or mixing or layering the slurry with a synthetic polymer solution. The liquid is subsequently driven off so as to form a foam. Porous implantable scaffolds fabricated by such a method are also disclosed.

Hybrid biologic/synthetic porous extracellular matrix scaffolds

The present invention provides a biomedical, biocompatible, polymeric foam scaffold suitable for use in the repair and regeneration of tissue and which contains located therein a network of, branched channels that are effective to encourage and facilitate vascularization and tissue growth within the scaffold and to methods for making such biomedical scaffolds.

Channeled biomedical foams an method for producing same

The present invention relates to a medical device, and more particularly to a method of forming a tubular membrane on a radially expandable structural frame. In one aspect, a structural frame is placed over a spinning mandrel and a fiber is electro-statically spun over at least a portion of the structural frame forming a membrane. A transfer sheath may be used between the mandrel and structural frame to prevent the electrostatically spun fiber from adhering to the mandrel. In another aspect, a first membrane is spun over the mandrel before the structural frame is placed over the mandrel. In this aspect, at least a portion of the structural frame is sandwiched between the membranes. The membrane or membranes and structural frame form a fiber spun frame assembly. The fiber spun frame assembly may be coated with an elastic polymer. In addition, the membrane or membranes may go through some post processing to achieve desired characteristics or configurations.

Method of placing a tubular membrane on a structural frame

Growing community of inventors

Princeton, NJ, United States of America

Iksoo Chun