Wave Life Sciences Ltd.

Ik-Hyeon Paik

Subramanian Marappan

David Charles Donnell Butler

Pachamuthu Kandasamy

Gopal Reddy Bommineni

Jayakanthan Kumarasamy

The present disclosure, among other things, provides technologies for oligonucleotide synthesis. In some embodiments, the present disclosure provides phosphoramidites and methods for synthesis thereof. In some embodiments, provided methods provides higher yields and/or purities. In some embodiments, provided methods remove byproducts without contact with an aqueous solution.

Compositions and methods for phosphoramidite and oligonucleotide synthesis

The present disclosure, among other things, provides technologies for preparing and purifying phosphoramidites for oligonucleotide synthesis.

Growing community of inventors

Needham, MA, United States of America

Ik-Hyeon Paik