Abbott Point of Care Inc.

Isoplexis Corporation

Other

New York University

Igor Nikonorov

Niten V Lalpuria

Darryn W Unfricht

Benjamin Ports

Kyle Hukari

Stephen C Wardlaw

Robert A Levine

John A Verrant

Robert Holt

Douglas R Olson

Sean MacKay

Colin Ng

Alaina Kaiser

Peter Tsiomplikas

John W Roche

John N Blum

Sean McCusker

Vu Phan

Patrick Paczkowski

Jeffrey M Whynall

Marek Turewicz

Ralph W Dowdell, Iii

Jerry Sedgewick

Sean Mccusker

Thomas J J Blanck

Robin A Levy

Embodiments of the current disclosure are directed to systems, methods and apparatus for evaluating single cell secretion profiles. In some embodiments, the apparatus may be configured to analyze substances expressed by a biological cell and may include a first compressible substrate, and a second substrate configured for removable sealing attachment with the first substrate. In some embodiments, upon attachment of the second substrate with the first substrate, an assembly is formed such that the open side of the plurality of chambers are covered by the second substrate, and a portion of each of the plurality of capture areas are exposed in each of the chambers.

Systems, devices and methods for cell capture and methods of manufacture thereof

A biological fluid analysis cartridge is provided. In certain embodiments, the cartridge includes a base plate extending between a sample handling portion and an analysis chamber portion. A handling upper panel is attached to the base plate within the sample handling portion. A collection port is at least partially formed with the handling upper panel. An initial channel and a secondary channel are formed between the handling upper panel and the base plate. The collection port and initial and secondary channels are in fluid communication with one another. A chamber upper panel is attached to the base plate within the analysis chamber portion. At least one analysis chamber is formed between the chamber upper panel and the base plate. The secondary channel and the analysis chamber are in fluid communication with one another.

Biologic fluid analysis cartridge with sample handling portion and analysis chamber portion

A biological fluid sample analysis cartridge is provided that includes a collection port and a body. The body has one or more internal channels in selective fluid communication with the collection port. The collection port includes a collection bowl, and a slide valve assembly operable to be selectively positioned in an open position and a closed position. In the open position, the collection bowl is accessible for sample deposition, and in the closed position the collection bowl is inaccessible for sample deposition.

Biologic fluid sample analysis cartridge with sample collection port

A biological fluid sample analysis cartridge, analysis system, and method for analyzing a biologic fluid sample are provided. The cartridge includes a collection port, at least one channel within the cartridge in fluid communication with the collection port, a passage in fluid communication with the at least one channel, and an analysis chamber mounted on a tray. The tray is mounted relative to the cartridge and selectively positionable relative to the passage in a first position where the analysis chamber will engage a bolus of sample extending out from the passage to permit selective transfer of sample from the bolus to the analysis chamber.

Biologic fluid sample analysis cartridge

An apparatus and method for analyzing a biological fluid sample is provided. The method includes the steps of: a) providing an analysis cartridge having a channel and an analysis chamber, wherein the channel is in fluid communication with the analysis chamber and includes at least one hydrophobic interior wall surface; b) admixing one or more anti-adsorption agents with fluid sample disposed within the channel, wherein the anti-adsorption agents are operable to inhibit adsorption of fluid sample onto the interior wall surface of the channel; c) moving the fluid sample into the analysis chamber; and d) analyzing the sample within the analysis chamber.

Apparatus and method using anti-adsorption agent to facilitate sample mixing and analysis

Described is a method and system for training medical professionals to perform a nerve block procedure. The system may include a nerve electrode at least partially inserted in a conductive gel and an NSMRD supplying a current signal to a needle which is inserted in the gel. The system may also include a processing arrangement which is connected to the NSMRD. The processing arrangement receives a transmitted current from the nerve electrode via the needle and measures a voltage drop. The measured voltage drop increases as a distance between the needle and the nerve electrode decreases.

System and method for training medical professionals to perform a nerve block procedure

A flying disk toy is provided with a streamer, windsock or the like for aesthetically enhancing the visual effect of the flying disk toy while in flight with minimal interference to its flight aerodynamics. The flying disk toy is in the form of a substantially disk-shaped body having an outer rim, a generally convex top surface, a generally concave bottom surface, and a central axis about which the body rotates when the disk toy is in flight. The streamer includes a leading end and a trailing end. The streamer may be illuminated while the disk toy is in flight. The streamer may also be positioned such that its leading end is adjacent to the outer rim of the disk body. If a hanger arm is employed to attach the streamer to the disk body, the hanger arm can be mounted in an anti-friction bearing position in the top surface of the disk body, whereby the hanger arm and the streamer are rotatable relative to the disk body.

Flying disk toy

Growing community of inventors

Whitestone, NY, United States of America

Igor Nikonorov