Nia Therapeutics, Inc.

University of California

Igor Izyumin

Benjamin Johnson

Rikky Muller

Bernhard Boser

Mitchell H Kline

Burak Eminoglu

Yu-Ching Yeh

Bernhard E Boser

Representative methods, apparatus and systems are disclosed for providing concurrent electrical stimulation and electrical recording in a human or non-human subject, such as for neuromodulation, with the apparatus coupleable to an electrode array. A representative apparatus is typically an integrated circuit including: stimulation circuits, recording circuits, and blocking circuits responsive to control signals to block the stimulation voltage or current on an electrode from a corresponding recording circuit, while other recording circuits may simultaneously record electrical signals from other electrodes and generate recorded data. A representative stimulation circuit may include current sources; a first multiplexer for current source selection; a second multiplexer for electrode selection; a switchable voltage offset circuit; a switchable grounding circuit; and a stimulation controller providing control signals to provide the electrical stimulation, such as biphasic or monophasic stimulation, and bipolar or unipolar stimulation. Off-chip communication, control, along with power and voltage level control, are also provided.

Neuromodulation apparatus, method and system

Representative methods, apparatus and systems are disclosed for providing concurrent electrical stimulation and electrical recording in a human or non-human subject, such as for neuromodulation, with the apparatus coupleable to an electrode array. A representative apparatus is typically an integrated circuit including: stimulation circuits, recording circuits, and blocking circuits responsive to control signals to block the stimulation voltage or current on an electrode from a corresponding recording circuit, while other recording circuits may simultaneously record electrical signals from other electrodes and generate recorded data. A representative stimulation circuit may include current sources; a first multiplexer for current source selection; a second multiplexer for electrode selection; a switchable voltage offset circuit; a switchable grounding circuit; and a stimulation controller providing control signals to provide the electrical stimulation, such as biphasic or monophasic stimulation, and bipolor or unipolar stimulation. Off-chip communication, control, along with power and voltage level control, are also provided.

A vibratory gyroscope system is described which utilizes a mechanical resonator having a first mode of vibration and an associated first natural frequency, and a second mode of vibration having an associated second natural frequency. The angular rate of motion input couples energy between the first and second modes of vibration. The gyroscope has driver circuits, sensors and actuators for the first and second modes. The invention utilizes a bias error shifting method which provides for shifting the bias error away from DC to a higher frequency, where it can be removed by low pass filtering. As a result of the inventive method, gyroscope systems can be produced with significantly lower bias error.

Continuous mode reversal for rejecting drift in gyroscopes

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Oakland, CA, United States of America

Igor Izyumin