Dune Medical Devices Ltd.

Dune Medical Ltd.

Iddo Geltner

Dan Hashimshony

Gil Cohen

Harel Golombek

Gal Aharonowitz

Orit Yarden

A sensor unit for use in measurements on a subject is presented. The sensor unit includes a near field electromagnetic sensor and a flexible signal transmission structure, which are integral with one another by means of at least one common continuous surface. The flexible signal transmission structure is constructed from a first layer including signal connection lines associated with sensor cells near field electromagnetic sensor and a second electrically conductive layer electrically coupled to the electrically conductive material of the sensor.

Electromagnetic sensor for use in measurements on a subject

A medical device including a tissue characterization probe having an elongated carrier for carrying an array of tissue characterization sensors arranged in a spaced-apart relationship at least along an axis of said carrier within at least a distal portion thereof, such that progression of the probe through a tissue mass provides for locating and determining a dimension of an abnormal tissue specimen inside said tissue mass based on characterization signals from the sensors in the array. The elongated carrier has two integral portions including said distal portion and a hollow portion extending between a proximal end of the carrier and said distal portion. The carrier is configured for passing a predetermined treatment tool through the hollow portion thereof and enabling at least a part of the treatment tool to project from the hollow portion and extend along the distal portion.

Medical device and method for use in tissue characterization and treatment

The present invention relates to a device for tissue-characterization, designed for effective sensor-to-tissue contact. The device includes an element, having a rigid surface of a linear cross-section, on which at least one sensor is arranged, and a mechanism for applying a force to a soft tissue, the line of force being at an acute angle with the rigid surface, for stretching or stretching and pushing the soft tissue against the rigid surface, thus achieving effective contact between the tissue and the at least one sensor. In consequence, the accuracy of the sensing is improved. In accordance with another embodiment, a plurality of sensors is employed, arranged along a curved element, for providing three-dimensional information regarding the tissue, for example, by small-scale computerized tomography.

Tissue-characterization probe with effective sensor-to-tissue contact

A device for tissue characterization, comprises a structure; a first mechanism, associated with the structure, configured for exerting a first force on a tissue, for fixing the tissue to the structure, so as to substantially immobilize the tissue; and a second mechanism, associated with the structure, configured for pressing a sensor against an external surface of the immobilized tissue, thereby exerting a second force on the immobilized tissue, wherein at least a component of the first force is in opposition to at least a component of the second force, forcing the immobilized tissue against the sensor, and forcing the sensor against the immobilized tissue, bringing about an effective contact between the sensor and the immobilized tissue.

Device for forming an effective sensor-to-tissue contact

A device and method are provided for tissue handling, while maintaining the in-vivo tissue orientation. The device includes a structure, configured for receiving and holding a tissue specimen, wherein the tissue specimen includes tissue positional references; and device positional references, associated with the structure, for fixing the orientation of the tissue specimen, when held by the device, so as to reflect the tissue specimen positional references.

Device and method for transporting and handling tissue

A measurement device is presented being configured to be connectable to an analyzer unit (including a network analyzer). The measurement device includes a measuring unit and a calibration and control unit connected to and integral with the measuring unit. The calibration and control unit is configured to enable connection of the measuring unit to the analyzer unit. The calibration and control unit includes a number of terminals of known RF reflection coefficients respectively and includes a memory utility carrying recorded data indicative of said RF reflection coefficients and recorded data indicative of RF transfer coefficients of the calibration and control unit. This configuration enables calculation of the RF response of the measuring unit while remaining integral with the calibration and control unit.

RF calibration device and method

A measurement system and method are provided for use in characterizing a tissue. The system comprises a probe adapted for operating in either a scan mode or a measure mode, and a control unit for operating the probe. The probe comprises a sensing module for measuring one or more parameters indicative of one or more states of the tissue; and an attachment module configured and operable to enable selective operation of the probe in either one of the scan mode and the measure modes. The control unit is configured and operative to selectively operate the probe in either one of the scan and measure modes.

Tissue-characterization system and method

The present invention relates to probes, systems, and methods for tissue characterization by its dielectric properties, wherein a physical feature of the probe is designed to define and delimit a tissue volume, at a tissue edge, where characterization takes place. Thus, the probe for tissue-edge characterization comprises: a first inner conductor, which comprises: proximal and distal ends, with respect to a tissue edge, along an x-axis; a first sharp edge, inherently associated with the proximal end; at least one feature, issuing from the first inner conductor, substantially at the proximal end, for forming at least one additional sharp edge, operative to enhance localized electrical fringe fields in the tissue, within a generally predefined tissue volume, at the tissue edge, the tissue volume being generally defined by physical parameters associated with the at least one feature; and a dielectric material, which encloses the conductor, in the y-z planes.

Probes, systems, and methods for examining tissue according to the dielectric properties thereof

An integrated tool is provided, having a tissue-type sensor, for determining the tissue type at a near zone volume of a tissue surface, and a distance-measuring sensor, for determining the distance to an interface with another tissue type, for (i) confirming an existence of a clean margin of healthy tissue around a malignant tumor, which is being removed, and (ii) determining the depth of the clean margin. The integrated tool may further include a position tracking device and an incision instrument. The soft tissue may be held within a fixed frame, while the tumor is being removed. Additionally a method for malignant tumor removal is provided, comprising, fixing the soft tissue within a frame, performing imaging with the hand-held, integrated tool, from a plurality of locations and orientations around the soft tissue, reconstructing a three-dimensional image of the soft tissue and the tumor within, defining a desired clean margin on the reconstructed image, calculating a recommended incision path, displaying the recommended path on the reconstructed image, and cutting the tissue while determining its type, at the near zone volume of the incision surface. The method may further include continuously imaging with the cutting, continuously correcting the reconstructed image and the recommended incision path, and continuously determining the tissue type, at the near zone volume of the incision surface.

Clean margin assessment tool

A sensor for tissue characterization is provided, comprising: a resonator, configured to be placed proximally to an edge of a tissue for characterization, without penetrating the tissue, the resonator comprising a conductive structure associated with a diameter-equivalent dimension D, in a plane substantially parallel with the edge, and with a feature size d; and at least one conductive lead, for providing communication with an external system, wherein the resonator is configured to resonate at a frequency which corresponds to a free-air wavelength range of between about lambda and about 40 lambda, wherein lambda is at least about ten times the diameter-equivalent D, and wherein upon receiving a signal in the range of between about lambda and about 40 lambda, the sensor is configured to induce electric and magnetic fields, in a near zone, in the tissue, the near zone having a diameter of about D, so that the tissue in the near zone effectively functions as part of the resonator, influencing its resonating values, and so the tissue in the near zone is thereby characterized by its electromagnetic properties, by the resonating response of the resonator.

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Herzlia, Israel

Iddo Geltner