Ajinomoto Co., Ltd.

Ichiro Noda

Konosuke Sano

Naohiko Yasuda

Koji Mitsugi

Kazuhiko Yamada

Fumihide Tamura

Tadashi Takemoto

Kenzo Yokozeki

Chikahiko Eguchi

Yasuo Ariyoshi

Fusayoshi Kakizaki

Keizo Matsuda

Kazushi Togo

Teruhiko Kagawa

The masking N-formyl group of an N-formyl-amino acid ester or N-formyl-peptide ester is removed without major side reactions when the ester is reacted in an inert liquid medium with hydroxylamine of which at least 70% is present in the form of a salt with a strong acid, the remainder, if any, being present as the free base or the salt of a weak acid.

Method of removing formyl groups from N-formyl-amino acid and

L-amino acids are produced by fermenting a hydantoin compound with Flavobacterium aminogenes or its enzymes.

Method for producing L-amino acid

A method for producing L-cysteine and/or L-cystine which comprises: A. holding 2-amino-thiazoline-4-carboxylic acid in an aqueous solution at a pH of 5 to 11 in the presence of an effective amount of enzyme produced by a microorganism; said enzyme being capable of converting the 2-amino-thiazoline-4-carboxylic acid to L-cysteine and/or L-cystine, and said microorganism being capable of growing in a medium containing 2-amino-thiazoline-4-carboxylic acid as a nitrogen source; and B. recovering the L-cysteine and/or L-cystine formed from said aqueous solution.

Method of producing L-cysteine and L-cystine

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Yokohama, Japan

Ichiro Noda