Ciba-geigy Corporation

Novartis Corporation

Ian Timothy Matthews

Nicholas Lowther

Ian Francis Hassan

Keith Allan Menear

Wilhelm Kump

Peter William Taylor

Jane I Lowrie

Desferrioxamine-B salts and their use as orally effective iron chelators

A salt of formula ##STR1## where X denotes a group of formula ##STR2## Y denotes a group of formula ##STR3## and R denotes the residue of an aliphatic or cycloaliphatic sulphonic acid having at least 3 carbon atoms after removal of a --SO.sub.3 H group therefrom.

Desferrioxamine-B salts

Compounds of the general formula: ##STR1## in which R is a lower alkyl group, and R.sub.1 is a tri-lower alkylmethylcarbonyl group, the structure elements --A.sub.1 --A.sub.2 --, A.sub.3 --A.sub.4 -- or A.sub.5 --A.sub.6 -- each represent ethylene or vinylene, or the elements --A.sub.1 --A.sub.2 -- and --A.sub.3 --A.sub.4 -- each represent ethylene and --A.sub.5 --A.sub.6 -- represents vinylene, their optical isomers and their salts exhibit valuable pharmaceutical properties.

Open chain rifamycin derivatives

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Horsham, United Kingdom

Ian Timothy Matthews