Medi-physics, Inc.

Princeton University

Ian Nelson

Bastiaan Driehuys

John Nouls

Zivko Djukic

Steve Kadlecek

Nicholas N Kuzma

Daniel Denton

Patrick Cella

A circuit for determining a polarization of a gas. The circuit includes a polarimetry circuit having an NMR coil that is configured to excite a polarized gas and that is responsive to an electromagnetic signal generated by the excited, polarized gas. The polarimetry circuit has a reproducible polarization measurement variability of less than about 2% when the NMR coil is exposed to a temperature in a range of about 0&#xb0; C. to about 200&#xb0; C.

Methods, systems, circuits and computer program products for determining polarization of a gas

A system for determining polarization of a gas comprises a container that contains the polarized gas. An oscillator circuit comprises an Nuclear Magnetic Resonance (NMR) coil that is positioned adjacent to the container. A pulse generator circuit is configured to generate an electrical pulse that may be transmitted to an optical cell through the NMR coil to excite the polarized gas responsive to a control processor. A Q-reduction circuit that is independent of the pulse generator circuit is configured to reduce oscillations in the oscillator circuit from the transmitted electrical pulse responsive to the control processor. A receive circuit is responsive to an electrical signal that is induced in the oscillator circuit due to the electromagnetic excitation of the polarized gas. The control processor is configured to determine the polarization of the gas based on the output signal of the receive circuit. A polarimetry circuit for determining polarization of a gas includes an NMR coil that may be configured to excite a polarized gas and be responsive to an electromagnetic signal generated by the excited, polarized gas. The polarimetry circuit has a reproducible polarization measurement variability of less than 2% when the NMR coil is exposed to a temperature in a range of about 0&#xb0; C. to about 200&#xb0; C. Moreover, circuit-to-circuit polarization measurement variability may be less than about 3%.

Methods, systems, circuits, and computer program products for determining polarization of a gas

A system for determining polarization of a gas comprises a container that contains the polarized gas. An oscillator circuit comprises an NMR coil that is positioned adjacent to the container. A pulse generator circuit is configured to generate an electrical pulse that may be transmitted to the optical cell through the NMR coil to excite the polarized gas responsive to a control processor. A Q-reduction circuit that is independent of the pulse generator circuit is configured to reduce oscillations in the oscillator circuit from the transmitted electrical pulse responsive to the control processor. A receive circuit is responsive to an electrical signal that is induced in the oscillator circuit due to the electromagnetic excitation of the polarized gas. The control processor is configured to determine the polarization of the gas based on the output signal of the receive circuit. A polarimetry circuit for determining polarization of a gas includes an NMR coil that may be configured to excite a polarized gas and be responsive to an electromagnetic signal generated by the excited, polarized gas. The polarimetry circuit has a reproducible polarization measurement variability of less than 2% when the NMR coil is exposed to a temperature in a range of about 0&#xb0; C. to about 200&#xb0; C. Moreover, circuit-to-circuit polarization measurement variability may be less than about 3%.

A device for simulating a sample of gas having a specific level of polarization when measured by a NMR pickup coil includes an active circuit loosely coupled to the NMR pickup coil. The active circuit responds as a hyperpolarized gas having the specific level of polarization when measured by the NMR pickup coil.

NMR transfer standard

An apparatus and a method for providing a magnetic holding field about a chamber for accumulating frozen Xe. The apparatus includes a magnetic field source and a yoke for supporting the magnetic field source about the chamber. The magnetic field source provides a magnetic holding field having a field strength of greater than 2 kiloGauss. The apparatus may further include yoke for coupling the magnetic holding field through a portion of the chamber.

Growing community of inventors

Chapel Hill, NC, United States of America

Ian Nelson