Thermo Fisher Scientific Oy

Thermo Fisher Scientific Baltics Uab

Thermo Fisher Scientific Gmbh

Ian Kavanagh

Devin Leake

Heli Haakana

Laura-Leena Kiiskinen

Glyn Ball

Transposon nucleic acids comprising a transposon end sequence and a calibration sequence for DNA sequencing in the transposon end sequence. In one embodiment, the transposon end sequence is a Mu transposon end. A method for the generation of DNA fragmentation library based on a transposition reaction in the presence of a transposon end with the calibration sequence providing facilitated downstream handling of the produced DNA fragments, e.g., in the generation of sequencing templates.

Transposon nucleic acids comprising a calibration sequence for DNA sequencing

A method for the generation of DNA fragmentation library based on a transposition reaction in the presence of a transposon end with an engineered cleaveage site providing facilitated downstream handling of the produced DNA fragments, e.g., in the generation of sequencing templates. Transposon nucleic acids comprising a transposon end sequence and an engineered cleaveage site located in the sequence, e.g., in Mu transposon end sequence, are disclosed.

Methods and transposon nucleic acids for generating a DNA library

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Lucerne, Switzerland

Ian Kavanagh