Theranos, Inc.

Labrador Diagnostics LLC

Biotrack, LLC

Syntex (u.s.a.) Inc.

Aclara Biosciences, Inc.

Syva Company

Other

Behringwerke Aktiengesellschaft

Monogram Biosciences, Inc.

Theranos IP Company, LLC

Ian Gibbons

Elizabeth A Holmes

Tammy Burd

Anthony Joseph Nugent

Shaunak Roy

Gary Frenzel

Robert S Hillman

Edmond Ku

Timothy Michael Kemp

Michael E Cobb

Paul Patel

Vladimir E Ostoich

Jimmy D Allen

Edwin F Ullman

Laura J Winfrey

Daniel L Young

Seth Gary Michelson

Anthony Delacruz

John K Howard

Chengwang Wang

Michael O'Connell

Shize Daniel Qi

Melissa Takahashi

Samartha Anekal

Chris Todd

Jeff Fenton

Keith Moravick

Adam Patrick Vollmer

Bruce Johnson

Thanh Dang

Douglas Matje

Uwe Springborn

Sharat Singh

Chinmay Pangarkar

Sunny Balwani

Gerald L Rowley

Andrew Drake

Richard D Armenta

Michael O'connell

Mark Dayel

Travis Boone

Channing R Robertson

Michael M Gorin

Malissa Takahashi

Gary J Ciambrone

Qifeng Xue

Pyare L Khanna

John P Kenney

Philip L Felgner

Robert F Zuk

Anthony J Ticknor

Shulin Zeng

Torleif Ove Bjornson

Herbert H Hooper

Randy M McCormick

Carl N Skold

John D Olson

Ahmed Chenna

Hilary Sue Lackritz

Litai Weng

Thomas M Houts

Ron Oral

Jeffrey Sugarman

Robert K DiNello

Vivian Xiao

Margaret Henson

Jim Allen

Hossein Salimi-Moosari

Torlief Bjornson

Swapna Joshi

Don Besemer

Tim Kemp

John Howard

Seth Michelson

Tony Nugent

Michael O'CONNEL

The present invention provides devices and systems for use at the point of care. The methods devices of the invention are directed toward automatic detection of analytes in a bodily fluid. The components of the device are modular to allow for flexibility and robustness of use with the disclosed methods for a variety of medical applications.

Modular point-of-care devices, systems, and uses thereof

This invention is in the field of medical devices. Specifically, the present invention provides portable medical devices that allow detection of analytes from a biological fluid. The methods and devices are particularly useful for providing point-of-care testing for a variety of medical applications.

Methods for the detection of analytes in small-volume blood samples

The present invention provides fluidic devices and systems that allow detection of analytes from a biological fluid. The methods and devices are particularly useful for providing point-of-care testing for a variety of medical applications.

Systems and methods of fluidic sample processing

This invention is in the field of medical devices. Specifically, the present invention provides fluidic systems having a plurality of reaction sites surrounded by optical barriers to reduce the amount of optical cross-talk between signals detected from various reaction sites. The invention also provides a method of manufacturing fluidic systems and methods of using the systems.

Fluidic medical devices and uses thereof

This invention is in the field of medical devices. Specifically, the present invention provides portable medical devices that allow real-time detection of analytes from a biological fluid. The methods and devices are particularly useful for providing point-of-care testing for a variety of medical applications. In particular, the medical device reduces interference with an optical signal which is indicative of the presence of an analyte in a bodily sample.

Reducing optical interference in a fluidic device

This invention is in the field of medical devices. Specifically, the present invention provides portable medical devices that allow real-time detection of analytes from a biological fluid. The methods and devices are particularly useful for providing point-of-care testing for a variety of medical applications.

Systems and methods of sample processing and fluid control in a fluidic system

Reagents, assays, methods, kits, devices, and systems for rapid measurement of cholesterol and cholesterol sub-fractions from a blood sample are provided. Total cholesterol, low density lipoprotein cholesterol, and high density lipoprotein cholesterol can be measured in a single assay using kinetic measurements, under conditions in which cholesterol sub-species are converted to a detectable product at distinct rates. The detectable product is measured at different times after assay initiation. A lipase, cholesterol esterase, cholesterol oxidase and a peroxidase may be used together to produce colored product in amounts directly proportional to the quantity of cholesterol converted. Methods for calculating very-low density lipoprotein cholesterol levels by further including triglyceride measurements are disclosed. Assays may be performed in a single reaction mixture, allowing more accurate and precise cholesterol determinations, including ratios of cholesterol sub-fractions to total cholesterol, at less expense, than would be expected by performing several different assays in different reaction mixtures.

Rapid, low-sample-volume cholesterol and triglyceride assays

The present invention provides systems, devices, and methods for point-of-care and/or distributed testing services. The methods and devices of the invention are directed toward automatic detection of analytes in a bodily fluid. The components of the device can be modified to allow for more flexible and robust use with the disclosed methods for a variety of medical, laboratory, and other applications. The systems, devices, and methods of the present invention can allow for effective use of samples by improved sample preparation and analysis.

Systems and methods for sample use maximization

The present invention provides an integrated health care surveillance and monitoring system that provides real-time sampling, modeling, analysis, and recommended interventions. The system can be used to monitor infectious and chronic diseases. When faced with outbreak of an infectious disease agent, e.g., influenza virus, the system can identify active cases through pro-active sampling in high risk locations, such as schools or crowded commercial areas. The system can notify appropriate entities, e.g., local, regional and national governments, when an event is detected, thereby allowing for proactive management of a possible outbreak. The system also predicts the best response for deployment of scarce resources.

Integrated health data capture and analysis system

The present invention provides system and methods for detecting an analyte indicative of an influenza viral infection in a sample of bodily fluid. The present invention also provides for systems and method for detection a plurality of analytes, at least two of which are indicative of an influenza viral infection in a sample of bodily fluid.

Real-time detection of influenza virus

Growing community of inventors

Portola Valley, CA, United States of America

Ian Gibbons