Consort Medical Limited

Anheuser-Busch Inbev S.a.

Ucb Biopharma Sprl

Bespak Europe Limited

Camcon Oil Limited

Ucbbiopharma Srl

Inbev S.a.

Ian Anderson

Alastair Mckean Willoughby

Rachel Suzanne Koppelman

Matt Ekman

Alastair Willoughby

Martin John McLoughlin

Neil Bentley Cammish

Ian Darnell

Joshua Daniel Stroobant

Douglas Ivan Jennings

Richard John Warby

Paul Allsop

Albert Marie Wauters

Edward Philip Duffy

Alan Judd

Peter Watson

Brad Howarth

Robert Glover

Marta Vilaplana

Stephen J Grimwade

Albert W Wauters

Martin John Mcloughlin

Edward P Duffy

Clive Graham Angel

Douglas Jennings

Joshua Stroobant

An assembly for an autoinjector device, the assembly including a syringe support for supporting a syringe by limiting forward axial movement of the syringe relative to the syringe support, and a guard element attachable to the syringe support by an attachment so that the guard element is axially restrained both axially forwardly and axially rearwardly relative to the syringe support by the attachment. Forwardly directed axial loads received by the guard element are transmitted to the syringe support via the attachment.

Assembly for an autoinjector device

A medicament delivery device comprises a housing and a syringe axially movable in the housing and the syringe having a barrel. The device further comprises a stopper axially movable in the barrel and which separates a first chamber and second chamber from one another. The stopper is axially movable in the barrel in response to a vapour pressure being received in the second chamber. The device also includes a biasing mechanism to axially move the syringe in the housing between a first syringe position and a second syringe position in response to a first reduction in the vapour pressure in the second chamber. In the first syringe position venting of the propellant from the second chamber through a first fluid pathway is permitted to enable the first reduction in the vapour pressure in the second chamber while venting of the propellant from the second chamber through a second fluid pathway is substantially prevented. In the second syringe position venting of the propellant from the second chamber through the second fluid pathway is permitted to enable a second reduction in the vapour pressure in the second chamber.

Medicament delivery device

A syringe assembly comprising a barrel for containing one or more medicaments, the barrel having a front outlet for allowing the expulsion of said one or more medicaments from the said barrel through said outlet, and a first stopper disposed in the barrel and axially moveable therein and defining a first volume in the barrel axially forwards of the first stopper and a second volume in the barrel axially rearwards of the first stopper. The first stopper has a two way valve that is moveable between a sealing configuration and an open configuration to selectively put the first volume in fluid communication with the second volume. The two way valve is moveable from the sealing configuration to the open configuration by an increase in fluid pressure in either of the first and second volumes. The syringe assembly additionally comprises a second stopper disposed in the barrel axially rearward of the first stopper and axially moveable therein, the second stopper providing a fluid tight seal at a rear end of the second volume. The syringe assembly further comprises a first plunger rod connected to the first stopper and extending axially rearwardly through the second stopper, the second stopper sealingly engaging with the first plunger rod but permitting axial sliding of the first plunger rod therethrough. The first plunger rod is axially moveable so as to axially move the first stopper and pressurise either of the first volume and second volume causing the two way valve to move into the open configuration and fluidly connect the first volume and second volume.

Mixing syringe assembly

A syringe propellable by propellant that boils at a predetermined temperature, the syringe including a barrel having an outlet at a front end, and a stopper axially moveable in the barrel. The stopper separates a first chamber and a second chamber, the first chamber being axially forwards of the stopper and being configured for containing a medicament, and the second chamber being axially rearwards of the stopper and being configured to receive propellant for acting on the stopper to move the stopper axially forwardly in the barrel to expel medicament through the outlet upon actuation of the syringe. The syringe further includes a third chamber for containing propellant. Upon actuation of the syringe, liquid propellant is released from the third chamber and boils outside of the third chamber at or above the predetermined temperature to provide an increasing vapor pressure in the second chamber that causes the stopper to move axially forwardly and begin to expel medicament through the outlet. At least one trigger for triggering an action is provided, the trigger activated in response to the pressure in the second chamber satisfying a predetermined condition.

Propellant powered syringe with trigger

A medicament delivery device () comprising a syringe () having a barrel with an open end, and an axially moveable stopper () received in the barrel separating a first chamber axially forwards of the stopper from a second chamber axially rearwards of the stopper. The medicament delivery device further including an expandable drive housing () arranged to receive a propellant from a propellant source () for providing a vapour pressure, the expandable drive housing having a narrow channel in fluid communication with the second chamber. The expandable drive housing is expandable upon receiving propellant from the propellant source and, upon expansion, causes forward axial movement of the syringe. Propellant introduced into the expandable housing may pass through the narrow channel into the second chamber and cause forward axial movement of the stopper in the barrel to expel medicament contained in the first chamber through the open end, where axial movement of the stopper in the barrel commences after axial movement of the syringe.

Medicament delivery device having gas propellant

A medicament delivery device including a first container having a delivery outlet at a front end thereof and a first stopper axially moveable in the first container, the first stopper defining and separating a first chamber and a second chamber in the first container, where the first chamber is axially forwards of the first stopper and the second chamber is axially rearwards of the first stopper. The medicament delivery device further includes a second container having a second stopper axially moveable in the second container, the second stopper defining and separating a third chamber and a fourth chamber in the second container, where the third chamber is axially forwards of the second stopper and the fourth chamber is axially rearwards of the second stopper, and where the third chamber has a vent outlet in fluid communication with a venting chamber.

A valved container assembly has a container for containing a fluid, extending in an axial direction, and having an open front end and a valve disposed in the container. A plunger element is disposed axially rearward of the valve and is axially moveable in the container. The plunger element is configured to increase the pressure of a fluid in a first volume of the container upon axial movement of the plunger element relative to the valve. The valve includes a channel bypassing a seal, the channel having a first opening in fluid communication with the atmosphere outside of the valved container assembly and a second opening selectively sealed from the first volume by a resilient seal. The resilient seal is moveable from a sealing configuration to an open configuration upon the pressure of the fluid in the first volume exceeding a first pressure threshold.

Valved container assembly

An assembly for an auto injector device, the assembly including a syringe support for supporting a syringe by limiting forward axial movement of the syringe relative to the syringe support, and a guard element attachable to the syringe support by an attachment so that the guard element is axially restrained both axially forwardly and axially rearwardly relative to the syringe support by the attachment. Forwardly directed axial loads received by the guard element are transmitted to the syringe support via the attachment.

A syringe propellable by a propellant that boils at a predetermined temperature, the syringe comprising a barrel having an outlet at a front end, a stopper axially moveable in the barrel, and a third chamber for containing propellant. The stopper defines and separates a first chamber and a second chamber, the first chamber being axially forwards of the stopper and being configured for containing a medicament, and the second chamber being axially rearwards of the stopper and being configured to receive propellant for acting on the stopper to move the stopper axially forwardly in the barrel to expel medicament through the outlet upon actuation of the syringe. The syringe is configured such that, in use, upon actuation of the syringe, liquid propellant is released from the third chamber and boils outside of the third chamber at or above the predetermined temperature to provide an increasing vapor pressure in the second chamber that causes the stopper to move axially forwardly and begin to expel medicament from the first chamber through the outlet. During forward axial movement of the stopper in the barrel, propellant vents away from the second chamber through a vent hole.

Venting syringe

A valved container assembly () comprising a container () for containing a fluid, the container () extending in an axial direction and having at least one venting opening () at a front end and at least one dispensing opening (). The valved container assembly () further comprising a valve () disposed in the container () and a plunger element () disposed axially rearward of the valve (), the plunger element () being axially moveable in the container () and defining a first volume () in the container () between the plunger element () and the valve (), where the plunger element () is configured to increase the pressure of a fluid in the first volume () upon axial movement relative to the valve (). The valve () comprises a permanent seal () forming a fluidic seal between the at least one venting opening () and the first volume (), and a resilient seal () that is axially rearward of said permanent seal () and is moveable between a sealing configuration and an open configuration. In the sealing configuration the resilient seal () forms a fluidic seal with the container () between the at least one dispensing opening () and the first volume (). In at least one axial position of the valve () in the container () when the resilient seal () is in the open configuration the first volume () is fluidly connected to the at least one dispensing opening (). The resilient seal () is moveable from the sealing configuration to the open configuration upon fluid pressure in the first volume () exceeding a predetermined pressure threshold.

A syringe assembly having a barrel for containing one or more medicaments and a stopper disposed in the barrel defining and separating a first volume and a second volume within the syringe assembly. The stopper includes a permanent seal fluidly sealing the stopper to the barrel about the entire perimeter of the stopper intermediate the first volume and second volume, and a channel bypassing the permanent seal, the channel having a first opening in fluid communication with the second volume and a second opening selectively sealed from the first volume by a resilient seal. The resilient seal is moveable between a sealing configuration and an open configuration to selectively seal the channel from the first volume and is moveable from the sealing configuration to the open configuration upon fluid pressure in the first volume or second volume exceeding a first pressure threshold.

Syringe assembly

A valved container assembly which has a container for containing a fluid, the container extending in an axial direction and having an open front end and a valve disposed in the container. The valved container assembly is configured so that forward axial movement of the valve relative to the container is inhibited. A plunger element is disposed axially rearward of the valve and is axially moveable in the container. The plunger element is configured to increase the pressure of a fluid in a first volume of the container upon forward axial movement relative to the valve. The valve includes a channel bypassing the permanent seal, the channel having a first opening in fluid communication with the atmosphere outside of the valved container assembly and a second opening selectively sealed from the first volume by a resilient seal.

Dispenser comprising actuating piston and outlet check valve

A valve for discharging a fluid, comprising:

Dispensing valves

A fluid injection device () for controlling injection of fluid into an oil-carrying tube in an oil well includes an inlet () for receiving the fluid; an outlet () for supplying the fluid for injection into the oil-carrying tube; an inlet valve () in a fluid path between the inlet and the outlet; an actuator () for opening and closing the valve; and a connector () for coupling the inlet to a fluid supply tube () extending between the device and a source of the fluid above the ground. A method of controlling injection of fluid using such a device is also provided.

Fluid injection device

A home beer dispensing apparatus has a keg having a self-contained bag filled with a beer and a pressure system. The pressure system creates a pressurized air space between the keg inner walls and the bag to assist in the dispensing of the beer. The pressure system has a keg one-way air valve mounted to a top wall of the keg to permit entry of pressurized air into the keg. The pressure system has a pressure reservoir mounted in the dispensing apparatus outside the keg and in fluid flow communication with the keg one-way valve. The reservoir stores a charge of pressurized air and supplies at least a portion of this charge to the keg through the keg air valve when the dispensing apparatus is operated to dispense the beer. The reservoir provides a reserved charge of pressurized gas that is on hand to reduce dampening pressure fluctuations during beer dispensing which can result in beer frothing, especially during the early stages of beer dispensing when the air head space in the keg is small. Further, the apparatus may also have a pressure sensing system adapted to measure time rate of pressure change in the keg. The apparatus has a signaling device responsive to the time rate of pressure change in the keg to produce a signal related to volume of beer remaining in the bag. Preferably, the signal is displayed visually on the dispensing apparatus.

Growing community of inventors

Burwell, United Kingdom

Ian Anderson