Other

National Cheng-Kung University

I-Ming Jou

Ming-Shi Chang

Fong-Chin Su

Po-Ting Wu

Li-Chieh Kuo

Wei-Jr Lin

Alleviating neural injury, such as spinal cord injury, in a subject (e.g., a human subject) in need of the treatment using an IL-20 antagonist, which can be an antibody that blocks a signaling pathway mediated by IL-20. Such antibodies include anti-IL-20 antibodies and anti-IL-20R antibodies that specifically block the IL-20 signaling pathway.

Use of IL-20 antagonists for alleviating spinal cord injury

An artificial implant for a carpometacarpal (CMC) joint used for replacing a CMC joint surface of the first metacarpal bone is provided and has: an insert portion having an inserting end for inserting into a bone marrow cavity exposed from an incision of the first metacarpal bone, and a front end; an articular replacement portion connected to the front end of the inserting portion and disposed outside the incision of the first metacarpal bone, and having an articular profile surface to replace the CMC joint surface of the first metacarpal bone; and an attached flange protruded from a peripheral of the articular replacement portion, attached to an outer bone surface of the first metacarpal bone adjacent to the incision, and having at least one suture hole, through which at least one suture passes for assisting to fix an abductor pollicis longus (APL) to the outer bone surface.

Artificial implant for carpometacarpal joint

Growing community of inventors

Tainan, Taiwan

I-Ming Jou