Kyungpook National University Industry-academic Cooperation Foundation

Hypoxi Co., Ltd.

Sun Mok Institute Education Foundation

Hyung Soo Han

Byung-Heon Lee

In-San Kim

In San Kim

Jae-Sung Bae

Jeong Soo Yoo

Jong Won Lee

Kyung Sik Song

Jung Hee Jang

Chae Ha Yang

Sun Ha Lim

Hee Kyoung Jin

Kyoung Ho Suk

Yae Sil Kim

Jae Chan Park

Dong Ick Rhee

The present invention relates to a peptide that passes through a blood-brain barrier and binds specifically to apoptotic cells in neurodegenerative brain disease-affected sites, and uses thereof. Therefore, the peptide of the present invention can be used for detecting and imaging apoptotic cells in neurodegenerative brain disease-affected sites, and for targeted drug delivery and theranosis of neurodegenerative brain diseases.

Peptide which passes through blood-brain barrier and targets apoptosis of neurodegenerative brain disease site and uses thereof

The present invention relates to stroke-targeting peptides and use thereof. More specifically, the present invention relates to a stroke-targeting peptide comprising an amino acid sequence selected from the group consisting of SEQ ID NO: 1 to SEQ ID NO: 4 and use thereof. The peptide of the present invention can be specifically bound to stroke cells in the subject, and thus can be effectively used in diagnostic markers and kits for stroke, and compositions for drug delivery specific to stroke and pharmaceutical compositions and compositions for imaging stroke.

Stroke-targeting peptide and use thereof

The present invention relates to a composition comprising a starch or total dietary fiber which improves the cell viability, specifically, the inventive starch and total dietary fiber isolated from the extract of Gramineae plant and the components therefrom improved the cell viability when the cells were incubated under hypoxic condition, or in the presence of beta-amyloid and 6-hydroxydopamine treatment, as well as prevented and treated myocardiac infarction, cerebral infarction and vascular dementia, or alleviated memory loss, all of which were proven using rats as the respective animal models. Therefore, they can be used as therapeutics or health care food for preventing and treating ischemic diseases or degenerative brain diseases.

Composition comprising starch or dietary fiber from gramineae plant for prevention and treatment of ischemic diseases and degenerative brain disease

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Daegu, South Korea

Hyung Soo Han