Korea Electronics Technology Institute

Dong-a St Co., Ltd.

Hyung-Keun Lee

Ji-Hoon Choi

Min-Jung Lee

Jin-Hyuk Kim

Weon-Bin Im

Jin-Woong Cho

Sun-Ho Choi

Sung-Hak Choi

Hyun-Jung Sung

Jung-Sang Park

Yun-Jae Won

Chong-Hwan Cho

Ho-Sang Moon

Jun-Hwan Moon

Seung-Hyun Song

Cheon-Hyoung Park

Yoon-Jung Kim

Jang-Yeon Lee

Hyeon-Seok Lee

The present disclosure relates to a novel tetrahydropyridine derivative compound, a stereoisomer thereof, or a pharmaceutically acceptable salt thereof, methods for preparing the compounds, methods for inhibiting UDP-3-O&#x2014;(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase (LpxC), methods for treating Gram-negative bacterial infections, the use of the compounds for the preparation of therapeutic medicaments for treating Gram-negative bacterial infections, and pharmaceutical compositions for prevention or treatment of Gram-negative bacterial infections, which contain the compounds. The compounds represented by formula I, stereoisomers thereof or pharmaceutically acceptable salts thereof according to the present disclosure can exhibit excellent effects on the treatment bacterial infections.

Tetrahydropyridine derivatives and their use as antibacterial agents

A joint detection-decoding receiver using a multistage parallel interference canceller for selectively estimating a partial codeword corresponding to a state transition (branch) is disclosed. The JDD receiver of the DS-CDMA system includes a PIC that employs a state sequence to selectively carry out a symbol estimation of a partial codeword corresponding to the branch so as to reduce complexity and a calculation load as well as maintaining a high performance of the receiver according to the joint detection-decoding.

Joint detection-decoding receiver of DS-CDMA system

Growing community of inventors

Seoul, South Korea

Hyung-Keun Lee