Chong Kun Dang Pharmaceutical Corporation

Samsung Electronics Co., Ltd.

Hyun-Mo Yang

Soyoung Kim

ChangSik Lee

Daekwon Bae

Nina Ha

Hyojin Lim

Young-Hoon Kim

Dohoon Kim

Jaeki Min

Hyeseung Song

Jaekwang Lee

Miseon Bae

Seung-Kee Moon

Changsik Lee

Soon-Kil Ahn

Daekyu Choi

Ho-Jin Choi

Nam-Song Choi

Jae-Kwang Lee

Soo-Jin Kim

Sung-Sook Lee

Sun-Ju Kong

Changkon Lee

Youngil Choi

Jungtaek Oh

Ilhyang Kim

Hojin Choi

Young-Min Kwon

Seongae Yoon

Young-Mi Kim

In-Taek Lim

Hyun-Jung Yu

Eunhee Ko

Jae-Su Shin

Provided are urea derivatives of Formula I: with histone deacetylase (HDAC) inhibitory activity, optical isomers thereof, pharmaceutically acceptable salts thereof and pharmaceutical compositions comprising the same. The provided urea derivatives of Formula I are selective histone deacetylase (HDAC) inhibitors and are effective for the treatment of histone deacetylase-mediated diseases such as malignant tumors, inflammatory diseases, rheumatoid arthritis, and neurodegeneration.

Compounds for selective histone deacetylase inhibitors, and pharmaceutical composition comprising the same

The present invention relates to novel azaindole derivatives, and more particularly, to novel azaindole derivatives having histone deacetylase (HDAC) inhibitory activity, isomers thereof, pharmaceutically acceptable salts thereof, hydrates thereof or solvates thereof, the use thereof for the preparation of pharmaceutical compositions, pharmaceutical compositions containing the same, a method of treating disease using the pharmaceutical compositions, and methods for preparing the novel azaindole derivatives. The novel azaindole derivatives according to the present invention are selective histone deacetylase (HDAC) inhibitors, and may be used as agents for treating malignant tumor diseases, inflammatory diseases, rheumatoid arthritis, and neurodegenerative diseases.

Azaindole derivatives as selective histone deacetylase (HDAC) inhibitors and pharmaceutical compositions comprising the same

Provided is a speaker module for a portable terminal which e includes a speaker housing having an opened front surface thus defining a resonance space, a radiation pattern disposed on a back surface of the speaker housing, and connection terminals which extend from the radiation pattern to be disposed in the resonance space, such that the radiation pattern is disposed on the speaker housing and the connection terminal for providing electric connection of the radiation pattern is disposed in an inner side of the speaker housing.

Speaker module for portable terminal

Disclosed herein are novel benzophenone derivatives represented by formula I, a pharmaceutically acceptable salt thereof, a hydrate thereof or a solvate thereof, a pharmacological composition containing the same, and a use of the composition as therapeutic drugs. The benzophenone derivatives have an inhibition activity of microtubule formation and can be used to treat a normal proliferative state of a malignant tumor by killing the actively proliferating cells.

Benzophenone derivatives useful for inhibiting formation of microtubule

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Gyeonggi-do, South Korea

Hyun-Mo Yang