Y-biologics Inc.

Intocell, Inc.

Hyun Mi Lee

Young Woo Park

Jae Eun Park

Bum-chan Park

Young-Gyu Cho

Jung Chae Lim

Si Hyung Lee

Bum-Chan Park

Soo Young Kim

Sung Ho Woo

Hyang Sook Lee

Sunyoung Kim

Jaeho Lee

Taekyo Park

Jongun Cho

Doohwan Jung

Sanghyeon Yun

Sangkwang Lee

Beomseok Seo

Okku Park

Suho Park

Donghoon Seo

Sena Kim

Minah Seol

Hyun Ju Lee

Youngja Song

Yeung Chul Kim

Gi Sun Baek

Hyun Kyung Lee

Hye-Nan Kim

Jisu Lee

Yosup Rew

Jina Song

Jihyeon Ha

Eun-Young Shim

Yunjung Ko

Jin Chui Youn

Eunjin Lee

Minju Lee

Soo A Choi

Jin Chul Youn

The present disclosure relates to antibody-drug conjugates (ADCs) wherein one or more active agents are conjugated to an anti-B7-H3 antibody through a linker. The linker may comprise a unit that covalently links active agents to the antibody. The disclosure further relates to monoclonal antibodies and antigen binding fragments, variants, multimeric versions, or bispecifics thereof that specifically bind B7-H3, as well as methods of making and using these anti-B7-H3 antibodies and antigen-binding fragments thereof in a variety of therapeutic, diagnostic and prophylactic indications.

Antibody-drug conjugates comprising anti-B7-H3 antibodies

Disclosed are an antibody to human programmed cell death 1 (PD-1) or an antigen-binding fragment thereof, a nucleic acid encoding the same, a vector including the nucleic acid, an isolated cell transformed with the vector, a method for producing the antibody or an antigen-binding fragment thereof, and a composition for preventing or treating cancer containing the same. The novel antibody binding to PD-1 or an antigen-binding fragment thereof can bind to PD-1 and inhibit the activity of PD-1, thus being useful for the development of immunotherapeutic agents for various diseases associated with PD-1.

Antibody to programmed cell death 1 (PD-1) and use thereof

Disclosed are an antibody to human programmed cell death-ligand 1 (PD-L1) or an antigen-binding fragment thereof, a nucleic acid encoding the same, a vector including the nucleic acid, a cell transformed with the vector, a method for producing the antibody or an antigen-binding fragment thereof, and a composition for preventing or treating cancer or infectious diseases containing the same.

Antibody to programmed death-ligand 1 (PD-L1) and use thereof

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Daejeon, South Korea

Hyun Mi Lee