Osong Medical Innovation Foundation, Korea University Research and Business Foundation

Korea Advanced Institute of Science and Technology

Snu Rdb Foundation

Hyun Koo Kim

Ji Ho Park

Yeon Ho Choi

Sung Hoi Hong

Yong In Park

Jae Min Jeong

Yun-Sang Lee

Yong Hwa Park

Jik Han Jung

Chan Hee Oh

Hye Sun Jeong

Daeho Jung

Byeong-Hyeon Choi

Yuhua Quan

Ji-Yun Rho

Byeong Hyeon Choi

Ji Young Lim

The present invention relates to a multi-column for isolating exosomes and an exosome isolation method, for isolating exosomes from a biological sample containing exosomes mixed with impurities such as lipoproteins and water-soluble proteins.

Multi-column for isolating exosomes and exosome isolation method

According to an embodiment of the present invention, a composition for diagnosing or predicting the prognosis of lung cancer is provided, the composition including a primer, probe, or antibody that specifically binds to a GRIP and coiled-coil domain-containing protein (GCC2) gene or protein in an exosome.

Marker composition for diagnosing or predicting prognosis of lung cancer based on exosome overexpressing GCC2 gene or protein

The present disclosure relates to a method for providing information for determining lung tumor through inhalation of a fluorescent contrast agent, more particularly to a method of inhaling a small amount of Indocyanine green. The present disclosure does not have the problem of the existing intravenous injection that the administered fluorescent contrast agent is distributed throughout the body. In addition, when comparing the cancer detection efficiency of inhalation administration and intravenous injection, the inhaled fluorescent contrast agent exhibits remarkably higher cancer detection effect than the intravenously injected fluorescent contrast agent.

Pharmaceutical composition for inhalation administration for labeling pulmonary tumorous lesion, containing fluorescent contrast agent as active ingredient

The present invention relates to a complex prepared by conjugating indocyanine green to mannosyl serum albumin in order to overcome shortcomings such as low light stability and low in vivo stability of indocyanine green that is a fluorescent dye reagent that is used during surgical operations, a preparation method thereof, an optical imaging probe comprising the same, and a kit comprising the probe.

Complex of mannosyl serum albumin, method of preparing the same, optical imaging probe and kit comprising the same

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Seoul, South Korea

Hyun Koo Kim