Yuhan Corporation

Hyok Jun Cho

Eun Kyung Kim

Hee Jae Tak

Cheol Hee Lim

Hyun Ho Choi

So Young Kim

Tae Dong Han

Sol Park

Na Ry Ha

Eui Chul Lee

Da Na Jeong

Na Yeon Yang

The present technology provides triazolones, tetrazolones, and imidazolones, or pharmaceutically acceptable salts thereof, preparation processes thereof, pharmaceutical compositions comprising the same, and uses thereof. The triazolones, tetrazolones, and imidazolones or their pharmaceutically acceptable salts exhibit inhibitory activity on VAP-1 and therefore can be usefully applied, e.g., for the treatment and prophylaxis of nonalcoholic hepatosteatosis (NASH).

Triazolones, tetrazolones, and imidazolones, or their salts, and pharmaceutical compositions comprising the same

The present technology provides 3,3-difluoroallylamines or pharmaceutically acceptable salts thereof, preparation processes thereof, pharmaceutical compositions comprising the same, and uses thereof. The 3,3-difluoroallylamines or their pharmaceutically acceptable salts exhibit potent inhibitory activity on VAP-1 and therefore can be usefully applied, e.g., for the treatment and prophylaxis of nonalcoholic hepatosteatosis (NASH).

3,3-difluoroallylamines or salts thereof and pharmaceutical compositions comprising the same

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Hwaseong-si, South Korea

Hyok Jun Cho