Other

Nexgen Biotechnologies, Inc.

Lee, Sun Kyo

Hyeong Il Kwon

Tae Hyun Kim

Seong Ran Lee

Tae Won Choi

Han Bong Ryu

Sun Kyo Lee

Jong Nam Choi

Tae Hwa Jeong

Woo Yeon Roh

A fusion protein has the amino acid sequence of SEQ ID NO: 5, SEQ ID NO: 6, SEQ ID NO: 7 or SEQ ID NO: 8. A composition having the fusion protein may improve skin wrinkle with increased anti-oxidant activity and skin cell proliferation effect. It can be advantageously used as a raw material of a functional cosmetic having an excellent skin regeneration effect like improvement of skin wrinkles and skin whitening.

Fusion protein comprising antifreeze protein and human epidermal growth factor with increased anti-oxidant activity and skin cell proliferation effect and cosmetic composition for anti-wrinkle comprising the same as effective component

A method for treating wrinkle or aging on a skin of a subject includes applying to the skin a composition that includes a green fluorescent protein-human epidermal growth factor fusion protein as an effective component. Since the fusion protein has an excellent anti-oxidation activity and a high skin cell proliferation effect, it can be advantageously used as a raw material of functional cosmetics having excellent skin regeneration effect like improvement of skin wrinkles and skin whitening.

Anti-wrinkle and anti-aging cosmetic composition comprising green fluorescent protein-human epidermal growth factor fusion protein as effective component

A botulinum toxin-human epidermal growth factor fusion protein with increased skin cell proliferation and anti-oxidation effect has the amino acid sequence of SEQ ID NO: 2, a gene consisting of() codon-optimized nucleotide sequence of SEQ ID NO: 1 for encoding the botulinum toxin-human epidermal growth factor fusion protein, a recombinant vector including the gene, a host cell transformed with the recombinant vector, and a method for producing a botulinum toxin-human epidermal growth factor fusion protein by transforming a host cell with the recombinant vector, and a cosmetic composition for regenerating skin and improving skin wrinkle including, as an effective component, a botulinum toxin-human epidermal growth factor fusion protein, and as the cosmetic composition has an effect of regenerating skin and improving skin wrinkle, it can be advantageously used in future in the field of cosmetics or cosmetic plastic surgery.

Botulinum toxin-human epidermal growth factor fusion protein with increased skin cell proliferation and anti-oxidation effect and cosmetic composition for regenerating skin and improving skin wrinkle comprising the same as effective component

A thermostable human epidermal growth factor-spider venom fusion protein with increased skin cell proliferation effect has the amino acid sequence of SEQ ID NO: 2, a gene ofcodon-optimized nucleotide sequence of SEQ ID NO: 1 for encoding the human epidermal growth factor-spider venom fusion protein, a recombinant vector including the gene, a host cell transformed with the recombinant vector, and a method for producing in a host cell a human epidermal growth factor-spider venom fusion protein by transforming a host cell with the recombinant vector, and a cosmetic composition for improving skin wrinkle and maintaining skin elasticity including a human epidermal growth factor-spider venom fusion protein, and as the cosmetic composition has excellent thermostability and has an effect of enhancing the activity of improving skin wrinkle and maintaining skin elasticity, it can be advantageously used in future in the field of cosmetics or cosmetic plastic surgery.

Thermostable human epidermal growth factor-spider venom fusion protein with increased skin cell proliferation effect and cosmetic composition for anti-wrinkle and maintaining elasticity of skin comprising the same as effective component

Growing community of inventors

Seoul, South Korea

Hyeong Il Kwon