Phi Biomed Co., Ltd.

The General Hospital Corporation

Postech Academy-industry Foundation

Hyemin Kim

Sei Kwang Hahn

Choun-Ki Joo

Seok-Hyun Yun

Keon Jae Lee

Yoon Keun Kim

Jun-Sub Choi

Eun Ju Oh

Dohee Keum

Jeong-A Yang

Ki Su Kim

Kitae Park

You Me Tae

Seung Kew Yoon

Eung-Sam Kim

Jeonga Yang

Kwan Yong Choi

Ji Hye Shin

Jung-Hee Kwon

Wonhee Hur

Ehsan Kamrani

One aspect of the present disclosure relates to a remotely controllable lens device. The lens device can include a lens material and a circuit physically coupled to the lens material. The circuit can be configured to be powered based on an energy signal from a power source to perform a function (e.g., release of drug, generation of electromagnetic radiation, detection of electromagnetic radiation, and/or control of an optical refractive property). For example, the power source can be an external power source and/or an auto-powered source. The external power source can be, for example, a power source that utilizes synchronized magnetic flux phase coupling (e.g., WiTricity). The auto-powered source can be provided on-site (e.g., on-chip) using a harvesting system (e.g., solar-cell, photo-cell, piezoelectric, etc.)

Remotely controllable lens device

A transdermal delivery system of drug and a method of preparing the same are provided. More specifically, the invention can be a transdermal delivery system applied for various protein drugs such as vaccines and chemical drugs, because the drug delivery system has a biocompatibility, biodegradation property, transdermal delivery property, the safety of human body, maximum activity of protein drugs, good bio-conjugation efficiency and a long-term efficacy, a method of preparing the same and its use.

Method for manufacturing transdermally delivered hyaluronic acid-protein conjugate and transdermally delivered hyaluronic acid-protein conjugate manufactured using same

The present invention relates to a drug delivery composition comprising a hyaluronic acid-peptide conjugate micelle and a production method thereof. According to the drug delivery composition and the production method of the drug-loaded, hyaluronic acid-peptide conjugate micelle of the present invention, the reaction for encapsulating can proceed in a mixed solvent of an aqueous solvent and an organic solvent. Therefore, the present invention can be applied to various types of water-insoluble active components and the biocompatible and biodegradable derivative can encapsulate a drug to provide a drug-loaded micelle, which is safe to be applied for human bodies. Moreover, the micelle has a therapeutic effect from the peptide contained therein, which can act in combination with the drug as packing therein. Therefore, the drug delivery composition and its production method can be utilized in the field of producing a sustained release formulation with an extended duration of the medicinal effect.

Drug delivery system using hyaluronic acid-peptide conjugate micelle

Growing community of inventors

Daegu, South Korea

Hyemin Kim