Medipost Co., Ltd

Hye Jin Jin

Miyeon Kim

Yoon-Sun Yang

Won Il Oh

Hong Bae Jeon

Soon-Jae Kwon

Wonil Oh

Soon-jae Kwon

Yoon Sun Yang

A pharmaceutical composition for the prevention or treatment of a pulmonary disorder is provided. The composition contains mesenchymal stem cells showing improved proliferation and differentiation capacity which are characterized by the expression or non-expression of one or more particular cell markers. Also, provided is a method for obtaining mesenchymal stem cells showing improved proliferation and differentiation capacity based on the expression or non-expression of such cell markers. The mesenchymal stem cells having improved proliferation and differentiation capacity can be easily obtained from mesenchymal stem cells of various origins based on the expression or non-expression of CD26, CD49f, CD146 and EGFR. The mesenchymal stem cells thus obtained can be effectively used for the prevention or treatment of a pulmonary disorder such as, for example, pulmonary emphysema.

Pharmaceutical composition for the prevention or treatment of a pulmonary disorder comprising mesenchymal stem cells having improved proliferation and differentiation capacity

A method for culturing mesenchymal stem cells. The method includes isolating mesenchymal stem cells having a size of 8 &#x3bc;m or less and culturing the mesenchymal stem cells in a medium containing calcium and magnesium and under a low oxygen condition. The method can significantly improve the proliferative capacity and differentiation potential of the mesenchymal stem cells.

Method for culturing mesenchymal stem cells according to cell size

Growing community of inventors

Seongnam-si, South Korea

Hye Jin Jin