Korea Research Institute of Chemical Technology

The Industry & Academic Cooperation in Chungnam National University (Iac)

Hye Eun Shim

Sun Woong Kang

Kang Moo Huh

Ik Sung Cho

Myeong Ok Cho

Han Chang Kang

The present invention relates to an organoid and, more specifically, to an organoid and a use thereof, the organoid being produced using a carrier for cell culture which comprises microcapsules containing gelatin, a natural polymer, an oil, and an oil thickener. When used as a carrier for cell culture in culturing cells, the microcapsules containing a natural oil, according to the present invention, have the effects of improving adhesion and survival of the cells and inducing maturation of the cultured cells. The organoid produced by culturing cells using the carrier for cell culture has been confirmed to have the function of the organ concerned and, when treated with a drug, react to the toxicity of the drug and thus may be variously employed in the development of new drugs, disease research, and the field of artificial organ development.

Organoid produced using carrier for cell culture, and method for evaluating drug toxicity using same

Disclosed is a spheroid forming culture container using a temperature-sensitive glycol chitosan derivative and a spheroid forming method using the same. In the disclosed spheroid forming culture container, a surface of a culturing space is coated with a glycol chitosan derivative having reversible sol-gel transition characteristic depending on temperature.

Spheroid forming culture container using temperature-sensitive glycol chitosan derivative, and spheroid forming method using same

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Daejeon, South Korea

Hye Eun Shim