Korea Research Institute of Bioscience and Biotechnology

Hyang Woo Lee

Hwan Mook Kim

Sun Young Kim

Bum Woo Park

Ji Duck Kim

Gyoon Hee Han

Jeom Yong Kim

Chang Woo Lee

Song Kyu Park

Hee Yoon Lee

Ki Hoon Lee

Jin Hyuk Yang

Dong Kyu Ryu

Tae Gyu Chun

Jin Ha Lee

Bong Yong Lee

Yung Hee Kho

Sang Bae Han

Jeung Whan Han

Kyunga Yu

Yong Kee Kim

The present invention is related to novel use of 2-oxo-heterocyclic compounds having anticancer activity and the process for preparing them and a pharmaceutical composition comprising the same. The present invention provides a pharmaceutical composition for preventing and treating the cancer disease comprising lung cancer, bone cancer, pancreatic cancer, skin cancer, cancer of the head and neck, cutaneous or intraocular melanoma, uterine cancer, ovarian cancer, rectal cancer or cancer of the anal region, stomach cancer, colon cancer, breast cancer, gynecologic tumors, Hodgkin's disease, cancer of the esophagus, cancer of the small intestine, cancer of the endocrine system, sarcomas of soft tissues, cancer of the urethra, cancer of the penis, prostate cancer, chronic or acute leukemia, solid tumors of childhood, lymphocytic lymphonas, cancer of the bladder, cancer of the kidney or ureter, or neoplasms of the central nervous system, therefore, it can be used as the therapeutics for treating and preventing cancer diseases.

2-oxo-heterocyclic compounds and pharmaceutical compositions

Growing community of inventors

Gyeonggi-do, South Korea

Hyang Woo Lee