Cj Cheiljedang Corporation

Korea Advanced Institute of Science and Technology

Samsung Electronics Co., Ltd.

Cmg Pharmaceutical Co., Ltd.

Handok Inc.

Cj Cheiledang Corporation

Cj Cheijedang Corporation

Hyang Choi

Soo An Shin

Young Wook Cho

Su Jin Choi

In Hye Kang

Min Tae Park

Hyung Joon Kim

Kyoung Min Lee

Hye Won Um

Sung Hoo Jhon

Si Yong Yang

So-Young Kim

Jun Ok Moon

Jung Min Choi

Hee Kyoung Jung

Hyun Jung Kim

Young Lyeol Yang

Jin-Ho Lee

Jin-ho Lee

Young-hoon Park

Hak Sung Kim

Jeong Seok Oh

Moonsoo Kim

Sang Mok Lee

Young-Hoon Park

Min Sun Kang

Han Won Lee

Song-Gi Ryu

Joong Jae Lee

Jae-yeong Ju

Eun-sung Koh

Ji-sun Lee

Chang-hyun Jin

Hyun Ho Kyeong

Hyo Deok Seo

Yunjung Choi

Sang Hee Park

Myung Eun Jung

Hyun Won Bae

Misoon Kim

Jeongbeob Seo

Jae Il Lee

Hyo Jeong Byun

Won-Joo Park

Gilnam Lee

MinWoo Lee

Eun-Sung Koh

Peter Lee

Cheolhwan Yoon

Song Gi Ryu

Jae-Yeong Ju

Je Hak Kim

Hankyul Jeong

Kinam Lee

Soongyu Choi

Kyung-Chang Lee

Chang-Hyun Jin

Nam Hyun Kim

Hye Kyoung Kim

Chaewoon Lee

Cheol Hwan Yoon

Minwoo Lee

Ki Nam Lee

Jay Hak Kim

The present disclosure relates to a microorganism producing L-lysine and a method for producing L-lysine by using the same. More specifically, the present disclosure relates to a microorganism of the genus, which is modified such that the activity of a protein involved in cell wall hydrolysis is inactivated in comparison with the endogenous activity thereof; and a method for producing L-lysine using the same.

Microorganism producing L-lysine and method for producing L-lysine using the same

The present disclosure relates to a microorganism producing L-lysine, and a method for producing L-lysine using the same.

Microorganism of the genusproducing l-lysine and a method for producing l-lysine using the same

Provided are a novel modified ornithine decarboxylase protein having improved putrescine productivity and a use thereof.

Microorganism for production of putrescine and methods for production of putrescine using the same

The present invention relates to a novel gluconate repressor variant, a microorganism containing the same, and a method for producing L-lysine using the same.

Gluconate repressor variant, microorganism containing the same producing L-lysine, and method for producing L-lysine

Modified ornithine decarboxylase protein and a use thereof

The present invention relates to a putrescine-producing microorganism and a method for producing putrescine using the same. To be more specific, the present invention is directed to a microorganism given the ability to produce putrescine which is generated by blocking a biosynthetic pathway from ornithine to arginine, increasing the intracellular level of glutamate, enhancing the biosynthetic pathway of ornithine from glutamate, and introducing extracellular ornithine decarboxylase; and a method for producing putrescine by using the microorganism.

Microorganisms for producing putrescine and method for producing putrescine using same

The disclosure provides novel chemical compounds represented by Formula I or a pharmaceutically acceptable salt, solvate, polymorph, ester, tautomer or prodrug thereof. The compounds can be used as an inhibitor of Trk and are useful in the treatment of pain, cancer, inflammation, neurodegenerative disease and certain infectious diseases.  In some compounds of Formula I, Q is &#x2014;CH&#x2550;CRC(O)NRR, &#x2014;C&#x2261;CC(O)NRR, or 

Fused ring heteroaryl compounds and their use as Trk inhibitors

The present invention relates to a recombinant microorganism having enhanced ability of producing putrescine at high yield, which is generated by weakening the activity of NCgl1469 in a microorganism ofgenus that is modified to produce putrescine, and a method for producing putrescine using the same.

Recombinant microorganisms with an improved productivity of putrescine and method for producing putrescine using the same

The present invention relates to a microorganism having an improved ornithine-producing ability, in which the biosynthetic pathway of arginine form ornithine is blocked, the intracellular glutamate level is increased, and the biosynthetic pathway of ornithine from glutamate is enhanced, and a method for producing ornithine using the microorganism.

Microorganisms having improved ornithine-producing ability and method for producing ornithine using the same

The present invention relates to avirulentvariants by inactivating virulence gene clusters of(SG), a main pathogen of avian salmonellosis, and various uses thereof notably in the production of-specific lytic bacteriophages, pharmaceutical compositions and feed additives.

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The present invention relates to a microorganism having L-tryptophan productivity and a method for producing L-tryptophan using the same. More precisely, the present invention relates to the recombinantstrain CJ600 (KCCM 10812P) having tryptophan productivity produced from the mutant form (KFCC 10066) ofhaving L-phenylalanine productivity, wherein tryptophan auxotrophy is released, L-phenylalanine biosynthesis is blocked but tryptophan productivity is enhanced by reinforcing the gene involved in tryptophan biosynthesis, and a method of producing L-tryptophan using the same.

Disclosed herein is a novel bacteriophage which has specific bactericidal activity against one or morebacteria selected from the group consisting of, andwithout affecting beneficial bacteria, in addition to showing excellent tolerance to acid, heat and desiccation. The novel bacteriophage of the present invention can be widely used as an active ingredient for therapeutic agents, animal feeds or drinking water, cleaners and sanitizers for preventing and treating the infectious diseases caused byorincluding salmonellosis,food poisoning, Fowl Typhoid, and Pullorum disease or for controlling thebacteria. The present invention also provides important insights into prevention and control strategies againstinfection and suggests that the use of bacteriophage can be a novel, safe, and effectively plausible alternative to antibiotics for the prevention ofinfection in poultry.

Bacteriophage and antibacterial composition comprising the same

The present invention relates to a novel bacteriophage, more particularly, a bacteriophage that has a specific bactericidal activity against, or, a composition for the prevention or treatment of infectious diseases including salmonellosis andfood poisoning caused by, Fowl typhoid caused by, and Pullorum disease caused by, which comprises the bacteriophage as an active ingredient, and an animal feed, drinking water, cleaner, and sanitizer which comprise the bacteriophage as an active ingredient. The present invention also provides important insights into prevention and control strategies againstinfection and suggests that the use of bacteriophage can be a novel, safe, and effectively plausible alternative to antibiotics for the prevention ofinfection in poultry.

Growing community of inventors

Anyang-si, South Korea

Hyang Choi