Korea Research Institute of Chemical Technology

Yonsei University

National Cancer Center

St Pharm Co., Ltd.

Kyung Nong Corporation

Hwan Jung Lim

Jung Nyoung Heo

Ki Young Kim

Sung Soo Kim

Hyuk Soo Lee

Bum Tae Kim

Sung Youn Chang

Seong Hwan Kim

Hyuk Jin Lee

Sang Jin Lee

Eun Sook Lee

Sang Joon Shin

Kyung Chae Jeong

Ho Kyung Seo

Kyung Ohk Ahn

Hyung Tae Bang

Uk Il Kim

Kwang Rok Kim

Hyuk Jae Lee

Sang Youn Park

Seong Jun Park

Ji Hye Yoon

Kyung Jin Kim

Joo Kyung Kim

Jong-Kwan Kim

Jong -Kwan Kim

The present disclosure provides the compound having inhibitory property against TNIK having a specific chemical structure or its pharmaceutically acceptable salt. The present disclosure also provides a composition comprising the compound or its pharmaceutically acceptable salt. The present disclosure also provides a medical use of the compound, its salt or the composition comprising the compound or its pharmaceutically acceptable salt for treating or preventing cancer. The present disclosure also provides a method of treatment or prevention of cancer comprising administering the compound, its salt or the composition comprising the compound or its salt to a subject in need of such treatment or prevention.

Compounds for inhibiting TNIK and medical uses thereof

Provided is a method for treating or preventing cancer, containing, as an active ingredient, a compound having a specific chemical structure and an activity of inhibiting the formation of a c-Myc/Max/DNA complex, or a pharmaceutically acceptable salt thereof.

Anticancer pharmaceutical composition

Hetero ring-fused phenyl compounds for inhibiting TNIK and medical uses thereof

Disclosed are novel compounds of specific chemical structures having inhibitory activity on c-Myc/Max/DNA complex formation or pharmaceutically acceptable salts thereof.

Compounds for inhibiting c-myc/max/DNA complex formation

The present invention relates to a novel imidazotriazinone or imidazopyrazinone derivative, a tautomer thereof, a stereoisomer thereof and their mixture, or a pharmaceutically acceptable salt thereof; and a pharmaceutical composition for preventing or treating a tankyrase-related disease, which contains the same as an active ingredient.

Imidazotriazinone or imidazopyrazinone derivatives, and use thereof

Compounds for inhibiting c-Myc/Max/DNA complex formation

The present invention relates to a novel triazolopyrimidinone or triazolopyridinone derivative, a tautomer thereof, a stereoisomer thereof and their mixture, or a pharmaceutically acceptable salt thereof; and a pharmaceutical composition for preventing or treating a tankyrase-related disease, which contains the same as an active ingredient.

Triazolopyrimidinone or triazolopyridinone derivatives, and use thereof

The invention relates to diaminoaryl derivatives substituted by carbamate, salts thereof and a pesticidal composition containing the same, which exhibit superior pest control effects against various insect pests of insect species, in particular against moths such as the diamondback moth or

Diaminoaryl derivatives substituted by carbamate and pesticidal composition containing same

Growing community of inventors

Daejeon, South Korea

Hwan Jung Lim