Bp Corporation North America Inc.

Hwai Chang

David B Weiner

Grace DeSantis

Connie Jo Hansen

Shaun Healey

Geoff Hazlewood

David Blum

Alexander Varvak

Thomas Todaro

Kristine Chang

Thomas Woodward

Charles Hancock

Scott W Beaver

The invention relates to enzymes having xylanase, mannanase and/or glucanase activity, e.g., catalyzing hydrolysis of internal &#x3b2;-1,4-xylosidic linkages or endo-&#x3b2;-1,4-ghicanase linkages; and/or degrading a linear polysaccharide beta-1,4-xylan into xylose. Thus, the invention provides methods and processes for breaking down hemicellulose, which is a major component of the cell wall of plants, including methods and processes for hydrolyzing hemicelluloses in any plant or wood or wood product, wood waste, paper pulp, paper product or paper waste or byproduct. In addition, methods of designing new xylanases, mannanases and/or glucanases and methods of use thereof are also provided. The xylanases, mannanases and/or glucanases have increased activity and stability at increased pH and temperature.

Xylanases, nucleic acids encoding them and methods for making and using them

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San Marcos, CA, United States of America

Hwai Chang