Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Centaurus Biopharma Co., Ltd.

Lianyungang Runzhong Pharmaceutical Co., Ltd.

Beijing Shenogen Pharma Group Ltd.

Shouyao Holdings (beijing) Co., Ltd.

Yuliang Li

Huting Wang

Yong Peng

Yan Zhu

Hui Zhang

Yongxin Han

Hong Luo

Dengming Xiao

Jijun Li

Zhe Wang

Yuandong Hu

Yinghui Sun

Fansheng Kong

Lei Zhang

Yu Wang

Lei Liu

Ling Yang

Hongjiang Xu

Yonggang Wang

He Wang

Qiong Wu

Xin Tian

Kun Meng

Ying Sun

Chang Lu

Yuanyuan Huang

Xianxing Shang

Zanping Wang

Qin Yan

Ruiyu Zhao

Jing Wang

Jiaojiao Wang

Mingji Jin

Lixin Fan

Dongliang Mo

Yeliu Wang

Weinan He

Dong Wei

Yongheng Wei

Shousong Cao

A SHP2 phosphatase allosteric inhibitor and a drug containing said inhibitor, the SHP2 phosphatase allosteric inhibitor having the structure shown in formula (I), and the use of an optical isomer compound of the SHP2 phosphatase allosteric inhibitor or a pharmaceutically acceptable salt thereof in the preparation of drugs for the treatment of tumor diseases.

SHP2 phosphatase allosteric inhibitor

The present invention relates to a iminosulfanone compound represented by formula (I) as a bromodomain protein inhibitor and a pharmaceutically acceptable salt thereof and to a preparation method, pharmaceutical composition, and medical use thereof.

Iminosulfanone compound as bromodomain protein inhibitor and pharmaceutical composition and medical use thereof

The present invention relates to a quinazoline derivative shown in formula (I) and a preparation method therefor, a pharmaceutical composition comprising the compound shown in formula (I), and an application of the compound in preparing drugs for curing and preventing tumors. The compound of the present invention can irreversibly prevent EGFR phosphorylation, and effectively depress signal transduction of cancer cells, and accordingly has higher anti-tumor activity in vitro and in vivo. 

Quinazoline derivative and preparation method therefor

The invention provides a compound represented by formula (I) which may modulate a kinase, and a pharmaceutical composition thereof, as well as the method for preventing or treating a protein kinase mediated disease or condition. 

Kinase modulating compounds, compositions containing the same and use thereof

The present disclosure relates to a compound of formula I, a pharmaceutical composition thereof and the use thereof as an anti-tumor drug. 

Compound of camptothecin and preparation and use thereof

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Beijing, China

Huting Wang