Imam Mohammad Ibn Saud Islamic University

Hussein Ba-Ghazal

Tarek Ahmed Yousef

Saad Shaaban

Ahmed A Al-Karmalawy

Marwa Sharaky

Mohamed Alaasar

Ayman Abo Elmaaty

A method of treating includes contacting cancer cells with a bis-(organoselanyl urea)aryl agent of Formula (I). The method includes effective inhibition of growth of cancer cells using the bis-(organoselanyl urea)aryl agent of Formula (I) as compared to doxorubicin

Organoselenium compound for treating cancer

A method of treating cancer including administering a bis-(organoselanyl urea)aryl agent having a Formula (I) to a subject with cancer. The method includes effective inhibition of growth of cancer cells using the compound of Formula (I) as compared to doxorubicin.

Bis urea-based organoselenium compound and method for treating cancer

A method for inhibiting proliferation of cancer cells includes contacting the cancer cells with a cytotoxic effective amount of an anticancer compound of Formula (I); where R1 to R8 are each independently selected from a group consisting of a hydrogen atom, a halogen atom, and an optionally substituted alkyl. The anticancer compound exhibits an ICof from 2 micrograms per milliliters (μg/ml) to 10 μg/ml for inhibiting the proliferation and inducing the apoptosis of cancer cells.

Method for inhibiting proliferation of cancer cells

A method for inhibiting proliferation of cancer cells includes contacting the cancer cells with a cytotoxic effective amount of an anticancer compound of where R1 to R8 are each independently selected from a group consisting of a hydrogen atom, a halogen atom, and an optionally substituted alkyl. The anticancer compound exhibits a growth inhibition percentage of about 90%.

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Riyadh, Saudi Arabia

Hussein Ba-Ghazal