Microvention, Inc.

Jenavalve Technology Gmbh

Sequent Medical, Inc.

Hussain S Rangwala

William Robert Patterson

Ronak Dholakia

Payam Saffari

Stefan G Schreck

Todd J Hewitt

Vincent Ming Hai Chow

Makensley Lordeus

John F Migliazza

Hung P Tran

Gregory Edwin Mirigian

Aaron Baldwin

Parker Milhous

Victoria E Carr-Brendel

Matthew J Fitz

Joseph Emery

Joseph Rye

John Vu

Daniel Hoit

Kevin Hang Tang Chu

A vascular prosthesis (e.g., stent), and packaging and delivery system to selectively deliver a vascular prosthesis are described. In some embodiments, the vascular prosthesis utilizes a low porosity and high porosity section, and the packaging and delivery system allows the prosthesis to be delivered such that the position of the low porosity and high porosity sections of the prosthesis can vary.

Stent and stent delivery

This disclosure relates to a heart valve with improved functionality and durability.

Heart valve mimicry

The disclosure relates to heart have prostheses with the reduced need of pacemaker implantation and improved means for positioning the replacement heart valve. In one aspect of the present disclosure, the stent scaffold of the valve prosthesis includes axially extending locators. The locators may be positioned within the cusp of the native aortic valve. Placement of the locators within the cusps may prevent further proximal movement of the stent scaffold into the left ventricle. By adjusting the location of the proximal end of the locators with respect to the proximal end of the stent scaffold, infra-annular placement of the stent scaffold in the aortic annulus may be assured. In another aspect, means for visualizing the positioning of replacement heart valves at an implant site inside an individual's body is disclosed.

Device and method with reduced pacemaker rate in heart valve replacement

Described herein are durable coatings, i.e. for medical devices, and methods of forming the coatings.

Durable surface coatings

Devices and methods for treatment of a patient's vasculature are described. Embodiments may include a permeable implant having a radially constrained state configured for delivery within a catheter lumen, an expanded state, and a plurality of elongate filaments that are woven together. The permeable implant may include a stiffer proximal portion that is configured to sit at the neck of an aneurysm. The stiffer proximal portion may include coils, stiffening elements, or reinforcement elements disposed about or associated with the filaments or woven together with the filaments.

Filamentary devices for treatment of vascular defects

Devices and methods for treatment of a patient's vasculature are described. Embodiments may include a device that includes a plurality of permeable shells connected by a plurality of coils, each coil connecting at least one pair of permeable shells. The plurality of coils may include an inert hydrogel core that absorbs water.

Devices having multiple permeable shells for treatment of vascular defects

Devices and methods for treatment of a patient's vasculature are described. Embodiments may include a permeable implant connected to an expandable stent through a plurality of wires. The permeable shell is configured for placement in an aneurysm and the expandable stent is configured for placement in a parent vessel proximal, near, or adjacent the aneurysm.

Devices for treatment of vascular defects

The present disclosure relates to medical devices including occlusion devices, clot retrieval systems, and stents. More particularly, the medical devices described herein measure characteristics for intravascular treatment sites. The medical devices may include pressure sensors and/or length sensors that may be used to determine the effectiveness of the medical devices during or after treatment. These sensors may be particularly helpful when used on an occlusion device or a clot removal device.

Medical devices with sensing characteristics for intravascular treatment sites and methods thereof

A clot retrieval device is disclosed. In some embodiments, the device utilizes augmented radiopacity to improve imaging, an internal tensioning member, a plurality of connected components useful to engage larger clots, and/or a distal end configuration designed to enhance clot retention.

Clot retrieval

A medical device is disclosed and may have a spiral shape structure that can function as a stent, such as a flow diversion stent to treat aneurysms. The medical device may have a spiral shape structure that can function as an occlusive device, for instance to occlude aneurysms. The medical device may include a shape setting structure to selectively adjust the shape of the medical device.

Medical device with enhanced shape characteristics

The disclosure relates to heart valve prostheses with the reduced need of pacemaker implantation and improved means for positioning the replacement heart valve. In one aspect of the present disclosure, the stent scaffold of the valve prosthesis includes axially extending locators. The locators may be positioned within the cusp of the native aortic valve. Placement of the locators within the cusps may prevent further proximal movement of the stent scaffold into the left ventricle. By adjusting the location of the proximal end of the locators with respect to the proximal end of the stent scaffold, infra-annular placement of the stent scaffold in the aortic annulus may be assured. In another aspect, means for visualizing the positioning of replacement heart valves at an implant site inside an individual's body is disclosed.

Devices and methods for treatment of a patient's vasculature are described. Embodiments may include a permeable implant such as a permeable shell or mesh having a radially constrained state configured for delivery within a catheter lumen, an expanded state, and a plurality of elongate filaments that are woven together. The permeable implant may include a stiffer proximal portion that is configured to sit at the neck of an aneurysm. The stiffer proximal portion may include additional mesh layers on either the inside or the outside of a first permeable shell. The distal portion of the device may be softer and deformable.

Growing community of inventors

Villa Park, CA, United States of America

Hussain S Rangwala