Ap Biosciences Inc.

Hung-Tsai Kan

Jeng-Horng Her

Ching-Hsuan Hsu

Jhong-Jhe You

Po-Lin Huang

Hsin-Ta Hsieh

Ting-Yi Chang

PO-Lin Huang

Provided are monospecific and bispecific proteins that bind specifically to OX40 and/or PD-L1. Exemplary proteins release the inhibition through PD-L1 and stimulate T cell through OX40. Exemplary polyvalent proteins comprise at least one OX40 binding site and at least one PD-L1 binding site. In certain embodiments, the binding sites may be linked through an immunoglobulin constant region. Anti-OX40 and anti-PD-L1 antibodies are also provided.

PD-L1 and OX40 binding proteins for cancer regulation

PD-L1 and OX40 binding proteins for cancer Regulation

Growing community of inventors

Taipei, Taiwan

Hung-Tsai Kan