Medtronic Corevalve LLC

Medtronic Cv Luxembourg S.a.r.l.

Transdigm, Inc.

Edwards Lifesciences Cardiaq LLC

Medtronics Corevalve LLC

Corevalve, Inc.

Hung Nguyen

Than Nguyen

MyKim Nguyen

Robrecht Michiels

Stanley Komatsu

Stan Komatsu

Georg Boertlein

J Brent Ratz

Arshad Quadri

Jacques Seguin

Jacques R Seguin

Yen Liao

Kalathi Thygarajan

Robert Michiels

Mykim Nguyen

Brent J Ratz

Robrecht Michielis

A heart valve prosthesis is provided having a self-expanding multi-level frame that supports a valve body comprising a skirt and plurality of coapting leaflets. The frame transitions between a contracted delivery configuration that enables percutaneous transluminal delivery, and an expanded deployed configuration having an asymmetric hourglass shape. The valve body skirt and leaflets are constructed so that the center of coaptation may be selected to reduce horizontal forces applied to the commissures of the valve, and to efficiently distribute and transmit forces along the leaflets and to the frame. Alternatively, the valve body may be used as a surgically implantable replacement valve prosthesis.

Heart valve prosthesis and methods of manufacture and use

A replacement heart valve can have an expandable frame configured to engage a native valve annulus. A valve body can be mounted onto the expandable frame to provide functionality similar to a natural valve. The valve body has an upstream end and a downstream end, and a diameter at the downstream end is greater than a diameter at the upstream end.

Replacement heart valve

Heart valve prosthesis

Methods for delivering a prosthetic heart valve include advancing a delivery catheter containing the prosthetic heart valve to a deployment native heart valve, advancing an inner core movably coupled to a restraining sheath of the delivery catheter to expose a first end of the prosthetic heart valve, and advancing the inner core and the restraining to expose a second end of the prosthetic heart valve. The delivery catheter can include a distal flange located at a distal end of an outer core of the catheter body, configured to restrict distal longitudinal displacement of the prosthetic heart valve, and a retaining structure located proximally from the distal flange along the outer core of the catheter body, configured to restrict proximal longitudinal displacement of the prosthetic heart valve.

Methods for delivering a self-expanding valve

A prosthetic valve assembly for use in replacing a deficient native valve comprises a replacement valve supported on an expandable prosthesis frame. The valve may be delivered transluminally or transmyocardially using a thorascopic or other limited access approach using a delivery catheter. Preferably, the initial partial expansion of the valve is performed against the native valve annulus to provide adequate anchoring and positioning of the valve as the remaining portions of the valve expand. The valve may be delivered using a retrograde or antegrade approach. When delivered using a retrograde approach, a delivery catheter with a pull-back sheath may be used, while antegrade delivery is preferably performed with a delivery catheter with a push-forward sheath that releases the proximal end of the valve first.

System and method for transapical delivery of an annulus anchored self-expanding valve

A shut off valve () is provided for use in an aircraft lavatory system () during maintenance sanitizing operations. The shut off valve includes an inlet passage () in intermittent fluid communication with an outlet passage () and a magnetic flapper body () movable between a rest position and a seal position between said inlet passage and said outlet passage. The flapper body is moved by a magnetic actuator () whereby upon placing said magnetic actuator within the proximity of the flapper body, the flapper body is moved form the rest position and, with the assistance of fluid flow within the valve, into the seal position, thus preventing fluid communication between the inlet passage and the outlet passage.

Lavatory service shut-off valve

A shut off valve is provided for use in an aircraft lavatory system during maintenance sanitizing operations. The shut off valve includes an inlet passage in intermittent fluid communication with an outlet passage and a magnetic flapper body movable between a rest position and a seal position between said inlet passage and said outlet passage. The flapper body is moved by a magnetic actuator whereby upon placing said magnetic actuator within the proximity of the flapper body, the flapper body is moved from the rest position and, with the assistance of fluid flow within the valve, into the seal position, thus, preventing fluid communication between the inlet passage and the outlet passage.

Lavatory service shut off valve

Growing community of inventors

Garden Grove, CA, United States of America

Hung Nguyen