Chemgen Corporation

Eli Lilly and Company

Vista Chemical Company

Humg-Yu Hsiao

Douglas W Fodge

David M Anderson

Lin Liu

James J LaLonde

Compositions suitable for oral administration to an animal comprising at least one immune stress-reducing enzyme in an amount effective to decrease the level of positive acute phase protein in an animal, increase the level of negative acute phase protein in an animal, and/or improve animal growth performance is provided, as are methods using such compositions. The compositions include animal feed compositions, liquid compositions other than animal feed, and solid compositions other than animal feed.

Enzymes for reduced immunological stress

Enzymes of a particular class, characterized by the ability to cleave a linkage that effects release of a cell-surface protein or carbohydrate, which does not contain an anti-infection agent, display significant anti-infectious activity. Upon oral administration, these enzymes are effective, for example, in the treatment of digestive tract infections in humans and in animals. In the latter, there are benefits of significantly improved growth rate, feed efficiency, and overall health.

Composition comprising beta-mannanase

Enzyme treatment

Hemicellulase use in feeds with low caloric content

Alkaline proteases that are stable in the presence of linear alkylbenzene sulfonates can be obtained from bacteria isolated from soil and by other means. The soils are collected from an alkaline environment which has been exposed to extremely high pH and/or detergent contamination. The proteases are at least twice as stable as Esperase.TM. when stored in commercial liquid detergents.

Alkaline proteases stable in heavy-duty detergent liquids

Growing community of inventors

Rockville, MD, United States of America

Humg-Yu Hsiao