Shanghai University of Engineering Science

Shanghai Modern Pharmaceutical Engineering Research Center Co., Ltd.

Shanghai Whittlong Pharmaceutical Institute

Huimin Hou

Chunping Yuan

Hao Wang

Weiyue Lu

Cao Xie

Xuefeng Hu

Hongmei Zhang

Zhengfang Wang

Yunmei Ren

Mingying Qian

Chunlin Luo

Song Wang

Huiping Zhang

Jihu Wang

Zhilan Chai

Cuicui Guo

Yamei Miao

The invention discloses a high-transparency, low-temperature processable cellulose acetate film and its preparation method. The high-transparency cellulose acetate film comprises, by weight percentage, the following raw materials: 75-85 parts of modified cellulose acetate, 12-20 parts of plasticizer, 2-6 parts of transparency agent, where the plasticizer and transparency agent are both composite additives. The preparation process involves uniformly blending all raw materials, followed by uniform mixing and drying, extrusion, granulation, drying, and casting, to obtain a high-transparency cellulose acetate film. The cellulose acetate film prepared by the above method utilizes the synergistic effect of the specific plasticizer and transparency agent, which not only significantly reduces the processing temperature but also results in a film with high light transmittance and low haze. The film exhibits good extensibility and flexibility, excellent antibacterial properties, and the process is simple, time-saving, and efficient, making it suitable for large-scale industrial production.

High-transparency, low temperature processable cellulose acetate film and method for preparing the same

A continuous skin packaging and coating apparatus and a coating method for tablets. The continuous skin packaging and coating apparatus comprises a lower coating film unreeling roller, a waste edge reeling roller, an upper coating film unreeling roller, a lower coating film heating component, an upper coating film heating component, a first mold provided with a first tablet placing hole, a second mold provided with a second tablet placing hole, a heat-sealing plate, a cutting component, a blank tablet implanting component, and an operating mesa. The lower coating film unreeling roller and the waste edge reeling roller are provided on either side of the operating mesa. The lower coating film heating component, the blank tablet implanting component, the upper coating film unreeling roller, the upper coating film heating component, the heat-sealing plate, and the cutting component are sequentially provided above the operating mesa. The first mold is provided under the operating mesa below the blank tablet implanting component. The second mold is provided under the operating mesa below the heat-sealing plate. The upper coating film heating component is provided below the upper coating film unreeling roller.

Continuous skin packaging and coating apparatus and coating method for tablets

A nano drug delivery system includes a biofilm-coated drug nanocrystal. A drug in a physical form of nanocrystal is directly used as a rigid supporting skeleton, and is filled in a biofilm. The nano drug delivery system has the advantages of high drug loading capacity, good biocompatibility, long systemic circulation time and drug sustained release.

Method for preparing biofilm-coated drug nanocrystal and application thereof

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Shanghai, China

Huimin Hou