Luoxin Pharmaceutical (shanghai) Co., Ltd.

Shandong Luoxin Pharmaceutical Group Stock Co., Ltd.

Genfleet Therapeutics (shanghai) Inc.

Genfleet Therapeutics Inc.

Luoxin Pharmaceutical Co., Ltd.

Huijun He

Charles Z Ding

Lihong Hu

Jianyu Lu

Jiaqiang Dong

Shuhui Chen

Tie-Lin Wang

Shenyi Shi

Weidong Li

Jian Li

Xu Zeng

Bin Shi

Lifang Wu

Zhijuan Chen

Wenqian Yang

Provided are a salt form of an estrogen receptor down-regulator, a crystalline form thereof, and a preparation method therefor

Salt form of estrogen receptor downregulator, crystalline form thereof, and preparation method therefor

Disclosed in the present invention are a crystal form and salt form of a TGF-&#x3b2;R1 inhibitor and a preparation method therefor, and further disclosed is an application of the crystal form and the salt form in preparation of medicines for treating cancers. 

Crystal form and salt form of TGF-&#x3b2;RI inhibitor and preparation method therefor

Disclosed are a crystal form of an estrogen receptor inhibitor and a preparation method therefor, in particular disclosed are a crystal form A of a compound of formula (I) and a preparation method therefor, and the use of the crystal form in the preparation of a drug for treating breast cancer. 

Crystal form of estrogen receptor inhibitor and preparation method therefor

Disclosed in the present invention is a type of indole substituted piperidine compounds as an estrogen receptor down-regulator. Specifically disclosed are a compound as shown in formula (I), a pharmaceutically acceptable salt, hydrate or prodrug thereof, a preparation method therefor, a pharmaceutical composition thereof, and a use thereof as an estrogen receptor down-regulator in the treatment of estrogen receptor positive breast cancers. 

Indolo substituted piperidine compound as estrogen receptor down-regulator

Disclosed is a new indole compound, in particular, the compound as shown in formula (I), and a preparation method, pharmaceutical composition and use thereof as an estrogen receptor down-regulator in preparing drugs for treating estrogen receptor-positive breast cancer. 

Substituted-indole-compounds as estrogen receptor down-regulators

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Shanghai, China

Huijun He