Jacobio Pharmaceuticals Co., Ltd.

Huifeng Han

Cunbo Ma

Panliang Gao

Di Kang

Shaojing Hu

Xinping Wu

Zilong Xu

This invention provides a compound of formula I, their synthesis and their use for treating a SHP2 mediated disorder. More particularly, this invention provides a pharmaceutical composition comprising the said compound.

Heterocyclic derivatives useful as SHP2 inhibitors

This invention relates to certain novel pyrazine derivatives (Formula I) as SHP2 inhibitors which is shown as formula I, their synthesis and their use for treating a SHP2 mediated disorder. More particularly, this invention is directed to fused heterocyclic group derivatives useful as inhibitors of SHP2, methods for producing such compounds and methods for treating a SHP2-mediated disorder. 

Growing community of inventors

Beijing, China

Huifeng Han