Entasis Therapeutics, Inc.

Eli Lilly and Company

Hui Xiong

Neil Bifulco

Bolin Geng

Hoan Huynh

Thomas Francois Durand-Reville

Janelle Comita-Prevoir

Brendan Chen

Shanta Bist

Satenig Guler

Liang Zhao

Ye Wu

Daemian Dussault

Shyamali Ghosh

Carey Horchler

Giorgio Attardo

Helen McGuire

Carey Lynn Horchler

Helen Mcguire

Helen Maureen Mcguire

Daemian David Dussault

Thomas Durand-Reville

The present invention provides a novel compound of the formula: methods of making this compound, methods of using this compound for tau imaging, and preparations of tau imaging formulations. 

Azetidine derivatives for tau imaging

The present invention is directed to compounds which are beta-lacatamase inhibitors. The compounds and their pharmaceutically acceptable salts, are useful in combination with beta-lactam antibiotics, or alone, for the treatment of bacterial infections, including infections caused by drug resistant organisms, including multi-drug resistant organisms. The present invention includes compounds according to formula (Ia): or a pharmaceutically acceptable salt thereof, wherein the values of R, R, Rand Rare described herein.

&#x3b2;-lactamase inhibitor compounds

Beta-lactamase inhibitor compounds

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Chesterbrook, PA, United States of America

Hui Xiong