Avaya Technology LLC

Arqule, Inc.

Big Bear Networks, Inc.

Lucent Technologies Inc.

Massachusetts Institute of Technology

Finisar Corporation

Hui Wu

Ron Jay Barnett

Mark Anthony Ashwell

Yanbin Liu

Zhengxiang Ma

Manish Tandon

Nivedita Namdev

Louis Thomas Manzione

Syed M Ali

Rocio Palma

Richard Franklin Schwartz

Ilya Alexander Korisch

Jean-Marc Lapierre

Eugene W Kelleher

Jianqiang Wang

Neil Westlund

Rui-Yang Yang

Marc E Hill

David Vensel

Sudharshan Eathiraj

Magdi Moussa

Jonathan C King

Jeffrey Link

Charles Joseph Buondelmonte

Yu Ju Chen

Jason J Hill

King Lien Tai

Paul Anthony Polakos

Arild T Kolsrud

Yee Leng Low

Ming-Ju Tsai

Anton Filikov

Chris Brassard

Steffi Koerner

Jonathan Paul King

Keith V Guinn

Audra Dalton

Thaddeus Wojcik

Dennis S France

Alfredo Carlos Anderson

Patrick M Hutchins

Thomas J Sleboda

Michael Zhong Xuan Wong

Rebecca J Carazza

Robb B Nicewonger

Jeff S Link

Richard F Schwartz

The present invention relates to substituted tricyclic pyrazolo-pyrimidine compounds and methods of synthesizing these compounds. The present invention also relates to pharmaceutical compositions containing substituted tricyclic pyrazolo-pyrimidine compounds and methods of treating cell proliferative disorders, such as cancer, by administering these compounds and pharmaceutical compositions to subjects in need thereof.

Substituted tricyclic pyrazolo-pyrimidine compounds

The present invention relates to substituted pyrrolo-aminopyrimidine compounds and methods of synthesizing these compounds. The present invention also relates to pharmaceutical compositions containing substituted pyrrolo-aminopyrimidine compounds and methods of treating cell proliferative disorders, such as cancer, by administering these compounds and pharmaceutical compositions to subjects in need thereof. The substituted pyrrolo-aminopyrimidine compounds have the following general formula: 

Substituted pyrrolo-aminopyrimidine compounds

The present invention relates to substituted heterocyclic compounds and methods of synthesizing these compounds. The present invention also relates to pharmaceutical compositions containing substituted heterocyclic compounds and methods of treating cell proliferative disorders, such as cancer, by administering these compounds and pharmaceutical compositions to subjects in need thereof.

Substituted heterocyclic compounds

The present invention relates to substituted benzo-pyrido-triazolo-diazepine compounds and methods of synthesizing these compounds. The present invention also relates to pharmaceutical compositions containing substituted benzo-pyrido-triazolo-diazepine compounds and methods of treating cell proliferative disorders, such as cancer, by administering these compounds or pharmaceutical compositions to subjects in need thereof.

Substituted benzo-pyrido-triazolo-diazepine compounds

The present invention relates to substituted 5,6-dihydro-6-phenylbenzo[f]isoquinolin-2-amine compounds and methods of synthesizing these compounds. The present invention also relates to pharmaceutical compositions containing substituted 5,6-dihydro-6-phenylbenzo[f]isoquinolin-2-amine compounds and methods of treating cell proliferative disorders, such as cancer, by administering these compounds and pharmaceutical compositions to subjects in need thereof.

Substituted 5,6-dihydro-6-phenylbenzo[F]isoquinolin-2-amine compounds

The present invention provides imidazooxazole and imidazothiazole compounds and their synthesis. The compounds of the present invention are capable of inhibiting the activity of RAF kinase, such as B-RAF. The compounds are useful for the treatment of cell proliferative disorders such as cancer.

RAF inhibitors and their uses

The invention discloses phase-shifters, modulators, and method that produces a smaller &#x3c0; by means of a field excitation using multiple electrodes. A negative signal is introduced that travels with the positive signal, which enhances the electric field significantly. The field enhancement is provided by the superposition of the fields accumulated from each electrode. A base or substrate material can be made from any compound having linear electro-optic properties, such as lithium niobate, lithium tantalite, potassium lithium niobate, potassium titanyl phosphate or gallium-arsenide. For lithium niobate, there are two possible orientations of electric field, z-cut orientation or x-cut orientation.

Dual-electrode traveling wave optical phase shifters and methods

The invention discloses phase-shifters, modulators, and method that produces a smaller &pgr; by means of a field excitation using multiple electrodes. A negative signal is introduced that travels with the positive signal, which enhances the electric field significantly. The field enhancement is provided by the superposition of the fields accumulated from each electrode. A base or substrate material can be made from any compound having linear electro-optic properties, such as lithium niobate, lithium tantalite, potassium lithium niobate, potassium titanyl phosphate or gallium-arsenide. For lithium niobate, there are two possible orientations of electric field, z-cut orientation or x-cut orientation.

Dual-electrode traveling wave optical modulators and methods

An integrated high-speed package comprising a package housing having a housing lip and connector having a center pin abutting along a bottom surface of the housing lip. For signal registration of a first substrate to the signal lead, the substrate is &ldquo;floated&rdquo; up to the housing lip, which provides an alignment reference to ensure that the top surface of the first substrate is aligned and in direct registration with the signal lead. In another embodiment, the center pin to substrate registration is provided at a top surface of a housing base. The housing base preferably comprises a first portion of a first height and a second portion of a second height. Accordingly, the housing base can accommodate substrates of different thickness while allowing a top surface of the first and a second substrate to be coplanar to facilitate signal registration there between.

High-speed package design with suspended substrates and PCB

An electrical connecting element is disclosed comprised of a dielectric substrate having two conductor paths disposed on opposite sides and being substantially aligned with one another. The electrical connecting element employs differential-mode signaling such that the first conductor path carries a signal of opposite polarity to the second conductor path. A virtual ground exists between the differential &plus; and &minus; lines that permits an otherwise &ldquo;groundless&rdquo; differential transmission line. The substantial alignment of the first and second conductor paths improves the space constraints, relative to conventional electrical connecting elements. The characteristic impedance of the disclosed differential transmission line depends on the width of the trace lines the thickness of the dielectric substrate.

Connector for differential-mode transmission line providing virtual ground

A new physical design for electronic devices ( ) comprises a multi-layer stacked assembly ( ) of a plurality of pan-shaped conductive units that form the layers of the assembly. Each unit is preferably formed from a single sheet of metal into which electronic components, such as an antenna array ( ) or a filter array ( ) of a transceiver, have been stamped, cut, or etched, and which is then bent around its periphery to form a pan shape. The pans are oriented to face the same direction, are stacked one on top of another, and are fixedly attached to each other by weld, solder, or adhesive. The electrical components defined by the different units are electrically interconnected in a connectorless manner, preferably by flanges ( ) formed in the same sheets of metal as the units themselves and extending between the units. Adjacent units in the stack define electromagnetically isolated chambers, e.g., for the filter array. Some layers perform double duty, e.g., a layer ( ) that forms a part of the chamber that houses the filter array also acts as a reflector plane for the antenna array.

Electronic stacked assembly

The invention discloses phase-shifters, modulators, and method that produces a smaller &pgr; by means of a field excitation using multiple electrodes. A negative signal is introduced that travels with the positive signal, which enhances the electric field significantly. The field enhancement is provided by the superposition of the fields accumulated from each electrode. A base or substrate material can be made from any compound having linear so electro-optic properties, such as lithium niobate, lithium tantalite, potassium lithium niobate, potassium titanyl phosphate or gallium-arsenide. For lithium niobate, there are two possible orientations of electric field, z-cut orientation or x-cut orientation.

Tri-electrode traveling wave optical modulators and methods

An apparatus and method for hermetically sealing, EMI shielding integrated circuits for high-speed electronic devices using a combination of microstrip to buried stripline interface for signal transmission from the integrated circuit. The packaging provided comprises a first plurality of microstrips interconnecting the integrated circuit to a plurality of buried striplines exposed on a surface of the main substrate. A ceramic interposer placed over the main substrate &ldquo;buries&rdquo; a portion of the exposed striplines on the main substrate to thereby insulate these signal paths from a hermetically sealing, and EMI shielding metal lid placed over the integrated circuit. The metal lid and the seal ring brazed over the ceramic interposer thus provide both a hermetic seal and an electric radiation block. A reduction in dispersion due to the buried striplines is also achieved, as well as improving jitter performance.

Apparatus and method for hermetically sealing and EMI shielding integrated circuits for high speed electronic packages

A high-frequency, e.g., microwave, filter ( ) is made, e.g., stamped or etched, from a single sheet ( ) of electrically conductive material, e.g., a metal plate or a printed circuit board. The sheet defines a frame ( ), one or more resonant filter elements ( ) inside of the frame, one or more supports ( ) connecting each resonant filter element to the frame, and a flange ( ) on one of the resonant filter elements. The flange serves as an electrical contact to the filter; another flange ( ) on another element, or the frame itself, serves as a second contact. An electrically conductive housing ( ) encapsulates both faces of the sheet.

Sheet-metal filter

A transceiver (,) comprises a stacked metal laminate assembly of a plurality of layers (,) inside an enclosure (,). A first layer (,) forms an antenna. A second layer (,) forms a ground plane for the antenna. A third layer (,) forms &ldquo;front-end&rdquo; filters (duplexer). A fourth layer (,) together with the second layer forms an electromagnetic isolation enclosure for the filters. A fifth layer (,) comprises a PC board with electronic circuits of the transceiver mounted thereon, and is both mounted to and electronically shielded by the fourth layer. Each of the first through fourth layers is preferably made from a single metal layer, such as a sheet of metal, by stamping. Each of the first through fourth layers is either bent along its periphery into a substantially &ldquo;cake-pan&rdquo; shape, or is flat and has a separate side wall (,) attached thereto. Flanges (,and,) that are unitarily formed with the filters extend through orifices (,and,) in the second and fourth layers to connect the filters with the antenna and the electronic circuits. The connections may be conductive or capacitive. The assembly is put together by stacking the first through fourth layers and then epoxying, soldering, or welding them together.

Transceiver stacked assembly

Growing community of inventors

Milpitas, CA, United States of America

Hui Wu