Kaohsiung Medical University

Hui-Ting Chen

Mei-Ling Ho

Je-Ken Chang

Cherng-Chyi Tzeng

Yin-Chih Fu

Gwo-Jaw Wang

Kuang-Chan Hsieh

Chai-Lin Kao

Chih-Kuang Wang

Yao-Hsien Wang

Rajalakshmanan Eswaramoorthy

Shun-Cheng Wu

Yan-Hsiung Wang

Hsin-Fang Chang

A method for treating low bone mineral density associated with osteopenia, osteoporosis, and other diseases is disclosed. The method comprises administrating a composition comprising a 3,5-dihydroxypentanoic acid derivative according to Formula I to a mammal. A compound of 3,5-dihydroxypentanoic acid derivative having a structure according to Formula I or Formula II is also disclosed. 

Analogs of 3,5-dihydroxypentanoate for bone formation

A series of peptides with divergent confirmations including structures of formula (1A), (1B), (2) and (3) are provided. In the formula, wherein U, G, A, B, R1, R2 and T are as defined in the specification. The divergent peptides disclosed in the present invention are characterized in a mineral binding affinity function. 

Conformations of divergent peptides with mineral binding affinity

A method for locally controlled release of an effective amount of PTH(1-34) by a hyaluronic acid based hydrogel that can injected intra-articularly for the treatment of osteoarthritis is provided.

Method for controlled release of parathyroid hormone from cross-linked hyaluronic acid hydrogel

A controlled release system and manufacturing method is provided. The method comprises providing a first aqueous solution containing a hydrophilic drug and an alkaline agent, providing an organic solution containing a hydrophobic molecule, providing a second aqueous solution containing a hydrophilic surfactant, mixing the first hydrophilic solution with the organic solution to form a first emulsion, and mixing the first emulsion with a second aqueous solution to form a second emulsion containing delayed-release microsphere.

Controlled release system and manufacturing method thereof

The disclosure provides a cell penetrating peptide. The cell penetrating peptide includes an amino acid sequence of D, in which D represents an aspartate residue and 2&#x2266;n&#x2266;15.

Anionic cell penetrating peptide and its use for intracellular delivery

Growing community of inventors

Kaohsiung, Taiwan

Hui-Ting Chen