Sanofi-a Ventis Deutschland Gmbh

Hui Li

Raymond W Kosley, Jr

Holger Heitsch

Stephanie Hachtel

Werngard Czechtizky

Stephen J Shimshock

Aleksandra Weichsel

Rosy Sher

Juergen Dedio

Carolina Lanter

Sven Grueneberg

The invention relates to compounds of the formula I: in which R1, R2, X, A, B, D and Y1 to Y4 have the meanings indicated in the claims, and/or a pharmaceutically acceptable salt and/or a prodrug thereof. Because of their properties as inhibitors of chemokine receptors, especially as CXCR2 inhibitors, the compounds of the formula I and the pharmaceutically acceptable salts and prodrugs thereof are suitable for the prevention and treatment of chemokine mediated diseases.

CXCR2 inhibitors

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Neshanic Station, NJ, United States of America

Hui Li