G.d. Searle & Company

Other

Pharmacia Corporation

Hui Li

Daniel Paul Becker

Clara I Villamil

Daniel L Flynn

Daniel P Getman

Gary A DeCrescenzo

Joseph J McDonald

Roger A Nosal

Norman A Abood

Lori A Schretzman

Brian M Bax

John Nicholas Freskos

Thomas E Barta

Susan Landis Hockerman

Terri L Boehm

Louis J Bedell

Deborah A Mischke

Robert M Heintz

Yvette M Fobian

Michael B Tollefson

Alan E Moormann

William F Vernier

Joseph Gerace Rico

Jeffery N Carroll

Susan C Howard

Nathan W Stehle

Steve A Kolodziej

Laurence J Hine

The present invention relates to a moveable image display system comprising a plurality of moveable display frames, capable of displaying images, a power transmitter and a data transmitter. There are no electrical connections between the moveable display frames and the data or power sources, however the moveable display frames are mechanically and electrically connected to each other. The moveable display frames are capable of moving relative to each other and are capable of moving together relative to the data and power sources.

Moveable image display system

A treatment process is disclosed that comprises administering an effective amount of an aromatic sulfone hydroxamic acid that exhibits excellent inhibitory activity of one or more matrix metalloprotease (MMP) enzymes, such as MMP-2, MMP-9 and MMP-13, while exhibiting substantially less inhibition at least of MMP-1 to a host having a condition associated with pathological matrix metalloprotease activity. Also disclosed are metalloprotease inhibitor compounds having those selective activities, processes for manufacture of such compounds and pharmaceutical compositions using an inhibitor.

Aromatic sulfone hydroxamic acid metalloprotease inhibitor

2-Amino-benzoxazinones for the treatment of viral infections

An aromatic sulfonyl alpha-cycloamino hydroxamic acid compound that inter alia inhibits matrix metalloprotease activity is disclosed as are a treatment process that comprises administering a contemplated aromatic sulfonyl alpha-cycloamino hydroxamic acid compound in a MMP enzyme-inhibiting effective amount to a host having a condition associated with pathological matrix metalloprotease activity.

Aromatic sulfonyl alpha-cycloamino hydroxamic acid compounds

2-amino benzoxazinones for the treatment of viral infections

Thioaryl sulfonamide hydroxamic acid compounds

A class of compounds for the treatment of viral infections. Compounds of particular interest are defined by Formula II ##STR1## wherein R.sup.28 is selected from (a) amino substituted with one or two radicals selected from alkyl, aralkyl, heterocycoalkyl, heterocyclo, and aryl, and (b) amino acid residues and derivatives thereof; wherein R.sup.29 is selected from hydrido, alkyl, halo, ##STR2## wherein R.sup.30 is selected from alkyl, alkoxy, alkylamino, carboxyalkyl, alkoxyalkyl, alkylaminoalkyl, cycloalkyl, heterocyclo, heterocycloalkyl, heterocycloalkoxy, alkylaminoalkoxy, alkylaminoalkylamino, heterocycloalkylamino, and N-aralkylamino; wherein R.sup.31 is alkyl; wherein R.sup.32 is alkyl and aryl; or a pharmaceutically-acceptable salt thereof.

2-amino-benzoxazinones for the treatment of viral infections

Method of using (H.sup.+ /K.sup.+)ATPase inhibitors as antiviral agents

Growing community of inventors

Vernon Hills, IL, United States of America

Hui Li