Industrial Technology Research Institute

Hui-Ju Shen

Wen-Pin Hsieh

Nien-Jen Chou

Chu-Hsuan Chen

Yu-Fang Yen

Yi-Ting Tung

Hui-Chu Hsieh

Fen-Fei Lin

Jing-Tsyr Lin

Hui-Ling Peng

Yi-Yen Yuan

A biosensor and a biological detection method are provided. The biosensor includes a substrate, a plurality of first and second electrodes in a strip shape, a material layer and a capture antibody. The substrate has a sampling region and a measuring region connected to the sampling region. The first and second electrodes are disposed on the substrate in the measuring region, and the first and second electrodes are arranged alternately with each other, wherein the first electrodes are connected in parallel with each other, and the second electrodes are connected in parallel with each other. The material layer is disposed on the substrate in the measuring region and covers the first and second electrodes, wherein the material layer has a channel exposing a portion of each of the first electrodes and a portion of each of the second electrodes, the channel is connected to the sampling region, and an extending direction of the channel is interlaced with an extending direction of the first electrodes and the second electrodes. The capture antibody is disposed on the first and second electrodes exposed by the channel.

Biosensor and biological detection method

The present disclosure provides a method for detecting an analyte concentration. The method includes providing a test strip, which includes a first electrode set including a first reaction area, a second electrode set including a second reaction area, and a reaction reagent layer disposed on the second reaction area. The method includes providing a blood sample and bringing the blood sample into contact with the first electrode set and the second electrode set, applying a first voltage to the first electrode set by voltammetry to obtain a first response value, calculating a hematocrit value according to the first response value, applying a second voltage to the second electrode set to obtain a second response value, and calculating the actual value of the analyte concentration by using the hematocrit value and the second response value.

Methods for measuring analyte concentration

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Hsinchu County, Taiwan

Hui-Ju Shen