Microsoft Technology Licensing, LLC

Systimmune, Inc.

Hui Huang

Rafael Lopez-Uricoechea

Eugene Seichi Lin

Brian Robert Kovacevich

Zeren Gao

Octavian Tony Ureche

Ole Olsen

Robert G Hawking

Daron Spektor

Omar H Shahine

Blair R Renshaw

Sarat Chandra Subramaniam

Peter Eberhardy

Alex Mark Semenko

Yi Zhu

Michael H Krause

Jonathan Alexander Bockelman

Greg S Friedman

Dong Xia

Kevin Kaiwon Lam

Yau Ning Chin

Bill Brady

David Jellyman

Sean Lamont Grant Livingston

Katrina Bykova

Zinaida A Pozen

Anne-Marie K Rousseau

Yu Liang

Alisa Yujin So

Haseeb Ahmed

Camilla Wang

Brandon Philip Zahl

Gang Zhai

Sean L G Livingston

Michael Scott Pierce

Anand B Iyer

Yunfei Shang

Kumneger T Zelalem

The application provides guidance and navigation control (GNC) proteins. In one embodiment, the guidance and navigation control (GNC) protein, comprising a binding domain for a T cell activating receptor, a binding domain for a tumor associated antigen, a bind domain for an immune checkpoint receptor, and a binding domain for a T cell co-stimulating receptor. The binding domain for the tumor associated antigen is not adjacent to the binding domain for the T cell co-stimulating receptor. In one embodiment, the binding domain for the T cell activating receptor is adjacent to the binding domain for the tumor associated antigen (TAA).

Guidance and Navigation Control proteins and method of making and using thereof

A computing system includes a processor and memory storing instructions executable by the at least one processor. The instructions, when executed, provide a user interface component that receives an indication of an external user with which to share an item of electronic content, a link generation component that generates a link to share the item of electronic content and identifies a communication endpoint associated with the external user, and an access control component that receives a request to access the item of electronic content using the link and, in response to the request, generates an access code that is communicated to the communication endpoint associated with the external user. The user interface component receives an access input, and the access control component grants access to the item of electronic content based on a determination that the access input includes the access code communicated to the communication endpoint associated with the external user.

External sharing with improved security

The techniques enable a device to identify a best suitable application to open a resource such as a file. The file can be shared via a link or can be attached to a communication. The link comprises a uniform resource locator (URL) or is in some way associated with an underlying URL. The URL includes a pattern, or a portion that identifies a domain (e.g., a hostname) and/or a portion that identifies a type of file that is to be accessed and opened. Upon activation of the link, the device analyzes the URL to determine the pattern. The device then obtains, from a service associated with the URL, a ranked list of applications that are authorized to open the file. Moreover, the device performs, at run-time, a negotiation with the service to determine which application is best suited to open the file.

Identifying the best suitable application to open a file shared via a link

A computing system is configured to provide access to electronic content. The computing system includes a processor, a data store, an access control system, and a user interface component. The data store is coupled to the processor and is configured to store the electronic content. The access control system control system is configured to selectively allow a requestor to access the electronic content based on a stored metadata setting that is associated with the link. The user interface component is configured to receive a setting change related to a share associated with the link and to persist metadata associated with the setting change.

Persistent mutable sharing of electronic content

In a computing device running multiple applications, a check is made as to whether a threshold value of multiple threshold values has been met. Each of the multiple threshold values is associated with a characteristic of one of the multiple applications or a characteristic of a resource of the computing device. If the threshold value has not been met, then the multiple applications are allowed to continue running on the computing device. However, if the threshold value has been met, then one or more of the multiple applications to shut down is selected based at least in part on the characteristic associated with the threshold value that has been met, and the selected application is shut down.

Application lifetime management

In accordance with one or more aspects, a storage volume is transformed into an encrypted storage volume or an unencrypted storage volume using a multi-phase process. One or more parts of the storage volume that have not yet been transformed are identified, and one or more parts of the storage volume that are allocated for use are identified. In a first phase of the multi-phase process, one or more parts of the storage volume that have not yet been transformed and that are allocated for use are transformed. In a second phase of the multi-phase process, after the first phase is finished, one or more parts of the storage volume that have not yet been transformed and are not allocated for use are transformed.

Multi-phase storage volume transformation

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Bellevue, WA, United States of America

Hui Huang