Amolifescience Co., Ltd.

Kollodis Biosciences, Inc.

Konkuk University Industrial Cooperation Corp

Hui-Gwan Goo

Chan Kim

Dong-Sik Seo

In Yong Seo

Song Hee Koo

Kyuwon Baek

Seonho Jang

Seung Hoon Lee

Ji Hyun Lee

In-Yong Seo

Sang-Jae Lee

Sang-eun Park

Sangjae Lee

Ssang-Goo Cho

Kyu-Won Baek

Bong-Jin Hong

Song-Hee Koo

Seung-Hoon Lee

Ji-Hyun Lee

Bongjin Hong

Gwang-Mo Yang

Seon-Ho Jang

Jihye Won

Chulbae Yoo

The present disclosure relates to a three-dimensional micro-environment structure for controlling cell behavior, a three-dimensional surface and an array for controlling cell behavior, and a method for manufacturing the three-dimensional micro-environment structure.

Three-dimensional micro-environment structure for controlling cell behavior, three-dimensional surface for controlling cell behavior, and method for manufacturing array and three-dimensional micro-environment structure

Described is a three-dimensional (3D) microenvironment presenting defined biochemical and physical cues that regulate cellular behavior and use of the microenvironment. A composition to form the 3D microenvironment is provided by combining one or more natural or synthetic polymeric materials and substrate proteins recombinantly or chemically functionalized with a variety of bioactive peptides such as extracellular matrix-derived or growth factor-derived peptides. Also described are devices and methods for screening for optimal combinations of the bioactive motifs in order to create an extracellular microenvironment that can regulate specific cellular behavior such as cell growth, proliferation, migration or differentiation.

Defined three dimensional microenvironment for cell culture

This disclosure provides for a three-dimensional (3D) microenvironment presenting defined physical or mechanical cues that regulate cellular behavior and use of the matrix. The disclosure also provides for devices and methods for screening for optimal combinations of physical and mechanical cues in order to create a microenvironment that can regulate specific cellular behavior such as cell growth, proliferation, migration or differentiation.

Defined three-dimensional microenvironment for stem cell

Growing community of inventors

Seoul, South Korea

Hui-Gwan Goo