Innogenetics N.v.

N.v. Innogenetics S.a.

Innogenetics, S.a.

Hugo Van Heuverswyn

Rudi Rossau

Geert Maertens

Lieven Jozef Stuyver

Eric Saman

Robert De Leys

Bart Vanderborght

Geert Jannes

Andre Van De Voorde

Bernard Delaey

Lucia Fransen

Jos Raymackers

Dirk Jacobs

Kathleen Devos

The invention relates to a process for genotyping any HCV isolate present in a biological sample, previously identified as being HCV positive, and for classifying said isolate according to the percentage of homology with other HCV isolates, comprising the steps of:

Process for typing of HCV isolates

The present invention relates to 16S-23S rRNA spacer sequences fromand their use in a method for detection and/or identification of. The invention further relates to a method for detection and identification ofin a sample, involving the steps of: (i) optionally releasing, isolating and/or concentrating the polynucleic acids present in the sample; (ii) optionally amplifying the 16S-23S rRNA spacer region, or a part thereof, with at least one primer pair; (iii) detecting the presence of a 16S-23S rRNA spacer sequence; and (iv) identifying thepresent in the sample from the nucleic acid(s) detected in the sample.

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The present invention relates to 16S-23S rRNA spacer sequences from Pseudomonas species and their use in a method for detection and/or identification of Pseudomonas species. The invention further it relates to a method for detection and identification of at least one Pseudomonas species, or for the simultaneous detection of several Pseudomonas species in a sample, involving the steps of: (i) optionally releasing, isolating and/or concentrating the polynucleic acids present in the sample; (ii) optionally amplifying the 16S-23S rRNA spacer region, or a part thereof, with at least one primer pair; (iii) detecting the presence of a 16S-23S rRNA spacer sequence; and (iv) identifying the Pseudomonas species present in the sample from the nucleic acid(s) detected in the sample.

Detection and identification of pseudomonas species using the 16S-23S rRNA spacer

The invention relates to a probe consisting of at least about 15 nucleotides from the spacer region between rRNA genes of a non-viral organism, particularly prokaryotic organism and more particularly bacteria, and preferably from about 15 nucleotides to about the maximum number of nucleotides of the spacer region and more preferably from about 15 to about 100 nucleotides to be used for the detection of non-viral microorganisms.

Hybridization probes derived from the spacer region between the 16S and 23S rRNA genes for the detection of non-viral microorganisms

Process for typing HCV isolates

The present invention relates to a method for detection and identification of at least one microorganism, or for the simultaneous detection of several microorganisms in a sample, involving the steps of: (i) if need be releasing, isolating or concentrating the polynucleic acids present in the sample; (ii) if need be amplifying the 16S-235 rRNA spacer region, or a part of it, with at least one suitable primer pair; (iii) hybridizing the polynucleic acids of step (i) or (ii) with at least one and preferably more than one of the spacer probes as mentioned in table la or equivalents of thereof, under the appropriate hybridization and wash conditions, and/or with a taxon-specific probe derived from any of the spacer sequences as represented in FIGS.,under the same hybridization and wash conditions; (iv) detecting the hybrids formed in step (iii) with each of the probes used under appropriate hybridization and wash conditions; (v) identification of the microorganism(s) present in the sample from the differential

Simulataneous detection, identification and differentiation of eubacterial taxa using a hybridization assay

Hybridization probes derived from the spacer region between the 16s and 23s RRNA genes for the detection of non-viral microorganisms

Described is a new variety of retrovirus designated HIV-3, also known as HIV-1 subtype O, samples of which are deposited in the European Collection of Animal Cell Cultures (ECACC) under V88060301. Further described are variants of the virus.

HIV-3 retrovirus and its use

An isolated and purified polypeptide having heparin binding properties with the amino acid sequence of SQ ID No: 1 and pharmaceutical compositions for treating skin wounds.

Growing community of inventors

Kalken, Belgium

Hugo Van Heuverswyn